Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTWILSTGMG PHEDKYAKHE RATFKKTYSS MKTLSLNHLT AKQHMLMALC RDISLLPPLT

70 80 90 100 110 120
YIFTSLRKAW RVSMRTSITL YEPQSLRDAF TYFWQKLNSA YDNNSSFEGA SQKAVNGDGK

130 140 150 160 170 180
DSLLLSALTT ARASEYLLCS LWCLVSLYLS YAILDSLMVR WIVKYSTVAA ILRMFSMSLI

190 200 210 220 230 240
IVTLELLLLS SLSPELDYFL HTWILISCVL TAVYIWQSYL TSDLRYIRNQ EGEVQEDTNV

250 260 270 280 290 300
PEETEDYEDG EDDADEDSHV VVADESTVDV PSNDSLSDNS DGGLFPVNRP SVSHSQSPKR

310 320 330 340 350 360
PKKYPKKAFN FTTKRTIDLY KITVLCVVPV GLASFITMLG LLRNLFIQRL DVEQLERILH


EMHPPA


References and documentation are available.

Number of amino acids: 366 Molecular weight: 41673.81 Theoretical pI: 5.63
Amino acid composition: 
Ala (A) 21 5.7% Arg (R) 17 4.6% Asn (N) 12 3.3% Asp (D) 23 6.3% Cys (C) 5 1.4% Gln (Q) 10 2.7% Glu (E) 20 5.5% Gly (G) 11 3.0% His (H) 9 2.5% Ile (I) 18 4.9% Leu (L) 51 13.9% Lys (K) 18 4.9% Met (M) 11 3.0% Phe (F) 12 3.3% Pro (P) 15 4.1% Ser (S) 40 10.9% Thr (T) 26 7.1% Trp (W) 7 1.9% Tyr (Y) 17 4.6% Val (V) 23 6.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 43 Total number of positively charged residues (Arg + Lys): 35 Atomic composition: Carbon C 1875 Hydrogen H 2938 Nitrogen N 482 Oxygen O 558 Sulfur S 16 Formula: C1875H2938N482O558S16 Total number of atoms: 5869 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 64080 Abs 0.1% (=1 g/l) 1.538, assuming all pairs of Cys residues form cystines Ext. coefficient 63830 Abs 0.1% (=1 g/l) 1.532, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 46.76 This classifies the protein as unstable. Aliphatic index: 97.49 Grand average of hydropathicity (GRAVY): -0.092