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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTYGGRDQQY NKTNYKSRGG DFRGGRNSDR NSYNDRPQGG NYRGGFGGRS NYNQPQELIK

70 80 90 100 110 120
PNWDEELPKL PTFEKNFYVE HESVRDRSDS EIAQFRKENE MTISGHDIPK PITTFDEAGF

130 140 150 160 170 180
PDYVLNEVKA EGFDKPTGIQ CQGWPMALSG RDMVGIAATG SGKTLSYCLP GIVHINAQPL

190 200 210 220 230 240
LAPGDGPIVL VLAPTRELAV QIQTECSKFG HSSRIRNTCV YGGVPKSQQI RDLSRGSEIV

250 260 270 280 290 300
IATPGRLIDM LEIGKTNLKR VTYLVLDEAD RMLDMGFEPQ IRKIVDQIRP DRQTLMWSAT

310 320 330 340 350 360
WPKEVKQLAA DYLNDPIQVQ VGSLELSASH NITQIVEVVS DFEKRDRLNK YLETASQDNE

370 380 390 400 410 420
YKTLIFASTK RMCDDITKYL REDGWPALAI HGDKDQRERD WVLQEFRNGR SPIMVATDVA

430 440 450 460 470 480
ARGIDVKGIN YVINYDMPGN IEDYVHRIGR TGRAGATGTA ISFFTEQNKG LGAKLISIMR

490 500 510 520 530 540
EANQNIPPEL LKYDRRSYGG GHPRYGGGRG GRGGYGRRGG YGGGRGGYGG NRQRDGGWGN


RGRSNY


References and documentation are available.

Number of amino acids: 546 Molecular weight: 60999.39 Theoretical pI: 8.90
Amino acid composition: 
Ala (A) 28 5.1% Arg (R) 48 8.8% Asn (N) 29 5.3% Asp (D) 37 6.8% Cys (C) 5 0.9% Gln (Q) 26 4.8% Glu (E) 31 5.7% Gly (G) 68 12.5% His (H) 8 1.5% Ile (I) 36 6.6% Leu (L) 34 6.2% Lys (K) 27 4.9% Met (M) 12 2.2% Phe (F) 15 2.7% Pro (P) 27 4.9% Ser (S) 29 5.3% Thr (T) 27 4.9% Trp (W) 7 1.3% Tyr (Y) 25 4.6% Val (V) 27 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 68 Total number of positively charged residues (Arg + Lys): 75 Atomic composition: Carbon C 2664 Hydrogen H 4185 Nitrogen N 795 Oxygen O 819 Sulfur S 17 Formula: C2664H4185N795O819S17 Total number of atoms: 8480 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 76000 Abs 0.1% (=1 g/l) 1.246, assuming all pairs of Cys residues form cystines Ext. coefficient 75750 Abs 0.1% (=1 g/l) 1.242, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.16 This classifies the protein as stable. Aliphatic index: 69.47 Grand average of hydropathicity (GRAVY): -0.726