ProtParam
User-provided sequence:
10 20 30 40 50 60
MTYSTVNINT PPPYLALASN EKLPTVLSIA GTDPSGGAGV EADVKTITAH RCYAMTCITA
70 80 90 100 110 120
LNAQTPVKVY SINNTPKEVV SQILDANLQD MKCDVIKTGM LTTAAIEVLH EKLLQLGENR
130 140 150 160 170 180
PKLVVDPVLV ATSGSSLAGK DIASLITEKI APFADILTPN IPECFKLLGE DREISKLRDI
190 200 210 220 230 240
FEVAKDLAKI TKCSNILVKG GHIPWNDEEG KYITDVLYLG AEQRFITFKG NFVNTTHTHG
250 260 270 280 290 300
TGCTLASAIA SNLARGYSLP QSVYGGIEYV QNAVAIGCDV TKETVKDNGP INHVYAIEIP
310 320 330 340 350 360
LEKMLSDECF TASDAVHKKP VKSSLNKIPG GSFYKYLINH PKVKPHWDSY VNHDFVRKVA
370 380 390 400 410 420
DGSLEPKKFQ FFIEQDYLYL VNYARISCIA GSKSPCLEDL EKELVIVECV RNGLCQHERR
430 440 450 460 470 480
LREEFGIKDP DYLQKIQRGP ALRAYCRYFN DVSRRGNWQE LVIALNPCLM GYVHALTKIK
490 500 510 520 530 540
DEVTAAEGSV YREWCETYSS SWCHEAMLEG EKLLNHILET YPPEKLDTLV TIYAEVCELE
550
ANFWTAALEY E
References and
documentation are available.
Number of amino acids: 551
Molecular weight: 61334.30
Theoretical pI: 5.63
Total number of negatively charged residues (Asp + Glu): 70
Total number of positively charged residues (Arg + Lys): 57
Atomic composition:
Carbon C 2746
Hydrogen H 4324
Nitrogen N 718
Oxygen O 823
Sulfur S 24
Formula: C
2746H
4324N
718O
823S
24
Total number of atoms: 8635
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 71250
Abs 0.1% (=1 g/l) 1.162, assuming all pairs of Cys residues form cystines
Ext. coefficient 70250
Abs 0.1% (=1 g/l) 1.145, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 34.64
This classifies the protein as stable.
Aliphatic index: 93.79
Grand average of hydropathicity (GRAVY): -0.157