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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTYSTVNINT PPPYLALASN EKLPTVLSIA GTDPSGGAGV EADVKTITAH RCYAMTCITA

70 80 90 100 110 120
LNAQTPVKVY SINNTPKEVV SQILDANLQD MKCDVIKTGM LTTAAIEVLH EKLLQLGENR

130 140 150 160 170 180
PKLVVDPVLV ATSGSSLAGK DIASLITEKI APFADILTPN IPECFKLLGE DREISKLRDI

190 200 210 220 230 240
FEVAKDLAKI TKCSNILVKG GHIPWNDEEG KYITDVLYLG AEQRFITFKG NFVNTTHTHG

250 260 270 280 290 300
TGCTLASAIA SNLARGYSLP QSVYGGIEYV QNAVAIGCDV TKETVKDNGP INHVYAIEIP

310 320 330 340 350 360
LEKMLSDECF TASDAVHKKP VKSSLNKIPG GSFYKYLINH PKVKPHWDSY VNHDFVRKVA

370 380 390 400 410 420
DGSLEPKKFQ FFIEQDYLYL VNYARISCIA GSKSPCLEDL EKELVIVECV RNGLCQHERR

430 440 450 460 470 480
LREEFGIKDP DYLQKIQRGP ALRAYCRYFN DVSRRGNWQE LVIALNPCLM GYVHALTKIK

490 500 510 520 530 540
DEVTAAEGSV YREWCETYSS SWCHEAMLEG EKLLNHILET YPPEKLDTLV TIYAEVCELE

550
ANFWTAALEY E


References and documentation are available.

Number of amino acids: 551 Molecular weight: 61334.30 Theoretical pI: 5.63
Amino acid composition: 
Ala (A) 43 7.8% Arg (R) 18 3.3% Asn (N) 27 4.9% Asp (D) 27 4.9% Cys (C) 17 3.1% Gln (Q) 13 2.4% Glu (E) 43 7.8% Gly (G) 32 5.8% His (H) 14 2.5% Ile (I) 38 6.9% Leu (L) 53 9.6% Lys (K) 39 7.1% Met (M) 7 1.3% Phe (F) 15 2.7% Pro (P) 27 4.9% Ser (S) 31 5.6% Thr (T) 35 6.4% Trp (W) 6 1.1% Tyr (Y) 25 4.5% Val (V) 41 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 70 Total number of positively charged residues (Arg + Lys): 57 Atomic composition: Carbon C 2746 Hydrogen H 4324 Nitrogen N 718 Oxygen O 823 Sulfur S 24 Formula: C2746H4324N718O823S24 Total number of atoms: 8635 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 71250 Abs 0.1% (=1 g/l) 1.162, assuming all pairs of Cys residues form cystines Ext. coefficient 70250 Abs 0.1% (=1 g/l) 1.145, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.64 This classifies the protein as stable. Aliphatic index: 93.79 Grand average of hydropathicity (GRAVY): -0.157