ProtParam
User-provided sequence:
10 20 30 40 50 60
MTYTLAILGC GVMGQALLSA IYNAPKAADE TAAAFYPSKI ITCNHDEPSA QQVTDLVETF
70 80 90 100 110 120
DESPNGIKVE STYGHNVSAV EEASVVLLGT KPFLAEEVLN GVKSVIGGKL LISLAAGWTI
130 140 150 160 170 180
DQLSQYTSTV CRVMTNTPAK YGYGCAVVSY SADVSKEQKP LVNELISQVG KYVELPEKNM
190 200 210 220 230 240
DAATALVGSG PAFVLLMLES LMESGLKLGI PLQESKECAM KVLEGTVKMV EKSGAHPSVL
250 260 270 280
KHQVCTPGGT TIAGLCVMEE KGVKSGIING VEEAARVASQ LGQKKK
References and
documentation are available.
Number of amino acids: 286
Molecular weight: 30131.80
Theoretical pI: 5.37
Total number of negatively charged residues (Asp + Glu): 30
Total number of positively charged residues (Arg + Lys): 24
Atomic composition:
Carbon C 1329
Hydrogen H 2163
Nitrogen N 343
Oxygen O 417
Sulfur S 16
Formula: C
1329H
2163N
343O
417S
16
Total number of atoms: 4268
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 19285
Abs 0.1% (=1 g/l) 0.640, assuming all pairs of Cys residues form cystines
Ext. coefficient 18910
Abs 0.1% (=1 g/l) 0.628, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 25.94
This classifies the protein as stable.
Aliphatic index: 96.12
Grand average of hydropathicity (GRAVY): 0.109