ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVADNIDAGV AIAVADQSSS PVGDKVELPA GNYILVGVDI DTTGRRLMDE IVQLAAYTPT 

        70         80         90        100        110        120 
DHFEQYIMPY MNLNPAARQR HQVRVISIGF YRMLKSMQTY KIIKSKSEIA ALKDFLNWLE 

       130        140        150        160        170        180 
QLKTKAGPSS DGIVLIYHEE RKFIPYMILE SLKKYGLLER FTASVKSFAN SINLAKASIG 

       190        200        210        220        230        240 
DANIKNYSLR KLSKILSTTK EEDAACSAST SGSGSGLGSG SSMVSDSVSI SPRDSTVTNG 

       250        260        270        280        290        300 
DDKQSSKNAV QGKRELFDGN ASVRAKLAFD VALQLSNSDG KPEPKSSEAL ENMFNAIRPF 

       310        320        330        340        350        360 
AKLVVSDVLE LDIQIENLER QNSFRPVFLN YFKTTLYHRV RAVKFRIVLA ENGFDLNTLS 

       370        380        390        400        410        420 
AIWAEKNIEG LDIALQSIGR LKSKDKAELL ELLDSYFDPK KTTVKPVVKG NSNNNNNYRR 

       430        440        450        460        470        480 
RNRRGGRQSV KDARPSSSPS ASTEFGAGGD KSRSVSSLPD STTKTPSPNK PRMHRKRNSR 

       490        500        510        520        530 
QSLGATPNGL KVAAEISSSG VSELNNSAPP AVTISPVVAQ PSPTPVAITA SN 

References and documentation are available.

Number of amino acids: 532

Molecular weight: 57974.71

Theoretical pI: 9.55

Amino acid composition: 
Ala (A)  46	  8.6%
Arg (R)  31	  5.8%
Asn (N)  34	  6.4%
Asp (D)  29	  5.5%
Cys (C)   1	  0.2%
Gln (Q)  16	  3.0%
Glu (E)  26	  4.9%
Gly (G)  31	  5.8%
His (H)   5	  0.9%
Ile (I)  31	  5.8%
Leu (L)  45	  8.5%
Lys (K)  40	  7.5%
Met (M)  10	  1.9%
Phe (F)  17	  3.2%
Pro (P)  27	  5.1%
Ser (S)  66	 12.4%
Thr (T)  25	  4.7%
Trp (W)   2	  0.4%
Tyr (Y)  14	  2.6%
Val (V)  36	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 55
Total number of positively charged residues (Arg + Lys): 71

Atomic composition:

Carbon      C	      2541
Hydrogen    H	      4119
Nitrogen    N	       727
Oxygen      O	       798
Sulfur      S	        11

Formula: C2541H4119N727O798S11
Total number of atoms: 8196

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    31860
Abs 0.1% (=1 g/l)   0.550, assuming all pairs of Cys residues form cystines


Ext. coefficient    31860
Abs 0.1% (=1 g/l)   0.550, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.70
This classifies the protein as unstable.



Aliphatic index: 83.98

Grand average of hydropathicity (GRAVY): -0.397