ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVAEVQKQAP PFKKTAVVDG IFEEISLEKY KGKYVVLAFV PLAFSFVCPT EIVAFSDAAK 

        70         80         90        100        110        120 
KFEDQGAQVL FASTDSEYSL LAWTNLPRKD GGLGPVKVPL LADKNHSLSR DYGVLIEKEG 

       130        140        150        160        170        180 
IALRGLFIID PKGIIRHITI NDLSVGRNVN EALRLVEGFQ WTDKNGTVLP CNWTPGAATI 

       190 
KPDVKDSKEY FKNANN 

References and documentation are available.

Number of amino acids: 196

Molecular weight: 21614.88

Theoretical pI: 6.74

Amino acid composition: 
Ala (A)  17	  8.7%
Arg (R)   6	  3.1%
Asn (N)  10	  5.1%
Asp (D)  12	  6.1%
Cys (C)   2	  1.0%
Gln (Q)   5	  2.6%
Glu (E)  12	  6.1%
Gly (G)  14	  7.1%
His (H)   2	  1.0%
Ile (I)  12	  6.1%
Leu (L)  18	  9.2%
Lys (K)  18	  9.2%
Met (M)   1	  0.5%
Phe (F)  11	  5.6%
Pro (P)  11	  5.6%
Ser (S)  10	  5.1%
Thr (T)   9	  4.6%
Trp (W)   3	  1.5%
Tyr (Y)   5	  2.6%
Val (V)  18	  9.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 24

Atomic composition:

Carbon      C	       987
Hydrogen    H	      1550
Nitrogen    N	       254
Oxygen      O	       284
Sulfur      S	         3

Formula: C987H1550N254O284S3
Total number of atoms: 3078

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    24075
Abs 0.1% (=1 g/l)   1.114, assuming all pairs of Cys residues form cystines


Ext. coefficient    23950
Abs 0.1% (=1 g/l)   1.108, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 21.54
This classifies the protein as stable.



Aliphatic index: 95.00

Grand average of hydropathicity (GRAVY): -0.105