ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVAPALLPEL WTEILVPICA VIGIAFSLFQ WYVVSRVKLT SDLGASSSGG ANNGKNGYGD 

        70         80         90        100        110        120 
YLIEEEEGVN DQSVVAKCAE IQTAISEGAT SFLFTEYKYV GVFMIFFAAV IFVFLGSVEG 

       130        140        150        160        170        180 
FSTDNKPCTY DTTRTCKPAL ATAAFSTIAF VLGAVTSVLS GFLGMKIATY ANARTTLEAR 

       190        200        210        220        230        240 
KGVGKAFIVA FRSGAVMGFL LAASGLLVLY ITINVFKIYY GDDWEGLFEA ITGYGLGGSS 

       250        260        270        280        290        300 
MALFGRVGGG IYTKAADVGA DLVGKIERNI PEDDPRNPAV IADNVGDNVG DIAGMGSDLF 

       310        320        330        340        350        360 
GSYAEASCAA LVVASISSFG INHDFTAMCY PLLISSMGIL VCLITTLFAT DFFEIKLVKE 

       370        380        390        400        410        420 
IEPALKNQLI ISTVIMTVGI AIVSWVGLPT SFTIFNFGTQ KVVKNWQLFL CVCVGLWAGL 

       430        440        450        460        470        480 
IIGFVTEYYT SNAYSPVQDV ADSCRTGAAT NVIFGLALGY KSVIIPIFAI AISIFVSFSF 

       490        500        510        520        530        540 
AAMYGVAVAA LGMLSTIATG LAIDAYGPIS DNAGGIAEMA GMSHRIRERT DALDAAGNTT 

       550        560        570        580        590        600 
AAIGKGFAIG SAALVSLALF GAFVSRAGIH TVDVLTPKVI IGLLVGAMLP YWFSAMTMKS 

       610        620        630        640        650        660 
VGSAALKMVE EVRRQFNTIP GLMEGTAKPD YATCVKISTD ASIKEMIPPG CLVMLTPLIV 

       670        680        690        700        710        720 
GFFFGVETLS GVLAGSLVSG VQIAISASNT GGAWDNAKKY IEAGVSEHAK SLGPKGSEPH 

       730        740        750        760        770 
KAAVIGDTIG DPLKDTSGPS LNILIKLMAV ESLVFAPFFA THGGILFKYF 

References and documentation are available.

Number of amino acids: 770

Molecular weight: 80819.96

Theoretical pI: 5.13

Amino acid composition: 
Ala (A)  93	 12.1%
Arg (R)  15	  1.9%
Asn (N)  23	  3.0%
Asp (D)  30	  3.9%
Cys (C)  12	  1.6%
Gln (Q)   9	  1.2%
Glu (E)  31	  4.0%
Gly (G)  82	 10.6%
His (H)   6	  0.8%
Ile (I)  66	  8.6%
Leu (L)  67	  8.7%
Lys (K)  33	  4.3%
Met (M)  21	  2.7%
Phe (F)  48	  6.2%
Pro (P)  26	  3.4%
Ser (S)  58	  7.5%
Thr (T)  50	  6.5%
Trp (W)   8	  1.0%
Tyr (Y)  24	  3.1%
Val (V)  68	  8.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 61
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      3698
Hydrogen    H	      5782
Nitrogen    N	       900
Oxygen      O	      1057
Sulfur      S	        33

Formula: C3698H5782N900O1057S33
Total number of atoms: 11470

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    80510
Abs 0.1% (=1 g/l)   0.996, assuming all pairs of Cys residues form cystines


Ext. coefficient    79760
Abs 0.1% (=1 g/l)   0.987, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 22.74
This classifies the protein as stable.



Aliphatic index: 105.05

Grand average of hydropathicity (GRAVY): 0.615