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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVAPTALKKA TVTPVSGQDG GSSRIIGINN TESIDEDDDD DVLLDDSDNN TAKEEVEGEE

70 80 90 100 110 120
GSRKTHESKT VVVDDQGKPR FTSASKTQGN KIKFESRKIM VPPHRMTPLR NSWTKIYPPL

130 140 150 160 170 180
VEHLKLQVRM NLKTKSVELR TNPKFTTDPG ALQKGADFIK AFTLGFDLDD SIALLRLDDL

190 200 210 220 230 240
YIETFEVKDV KTLTGDHLSR AIGRIAGKDG KTKFAIENAT RTRIVLADSK IHILGGFTHI

250 260 270
RMARESVVSL ILGSPPGKVY GNLRTVASRL KERY


References and documentation are available.

Number of amino acids: 274 Molecular weight: 30331.56 Theoretical pI: 9.06
Amino acid composition: 
Ala (A) 16 5.8% Arg (R) 18 6.6% Asn (N) 10 3.6% Asp (D) 23 8.4% Cys (C) 0 0.0% Gln (Q) 5 1.8% Glu (E) 16 5.8% Gly (G) 20 7.3% His (H) 6 2.2% Ile (I) 18 6.6% Leu (L) 24 8.8% Lys (K) 25 9.1% Met (M) 5 1.8% Phe (F) 9 3.3% Pro (P) 12 4.4% Ser (S) 19 6.9% Thr (T) 24 8.8% Trp (W) 1 0.4% Tyr (Y) 4 1.5% Val (V) 19 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1332 Hydrogen H 2179 Nitrogen N 381 Oxygen O 415 Sulfur S 5 Formula: C1332H2179N381O415S5 Total number of atoms: 4312 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 11460 Abs 0.1% (=1 g/l) 0.378 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.05 This classifies the protein as stable. Aliphatic index: 85.73 Grand average of hydropathicity (GRAVY): -0.498