ProtParam
User-provided sequence:
10 20 30 40 50 60
MVAPTALKKA TVTPVSGQDG GSSRIIGINN TESIDEDDDD DVLLDDSDNN TAKEEVEGEE
70 80 90 100 110 120
GSRKTHESKT VVVDDQGKPR FTSASKTQGN KIKFESRKIM VPPHRMTPLR NSWTKIYPPL
130 140 150 160 170 180
VEHLKLQVRM NLKTKSVELR TNPKFTTDPG ALQKGADFIK AFTLGFDLDD SIALLRLDDL
190 200 210 220 230 240
YIETFEVKDV KTLTGDHLSR AIGRIAGKDG KTKFAIENAT RTRIVLADSK IHILGGFTHI
250 260 270
RMARESVVSL ILGSPPGKVY GNLRTVASRL KERY
References and
documentation are available.
Number of amino acids: 274
Molecular weight: 30331.56
Theoretical pI: 9.06
Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 43
Atomic composition:
Carbon C 1332
Hydrogen H 2179
Nitrogen N 381
Oxygen O 415
Sulfur S 5
Formula: C
1332H
2179N
381O
415S
5
Total number of atoms: 4312
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 11460
Abs 0.1% (=1 g/l) 0.378
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 33.05
This classifies the protein as stable.
Aliphatic index: 85.73
Grand average of hydropathicity (GRAVY): -0.498