ProtParam
User-provided sequence:
10 20 30 40 50 60
MVATSSKRTL DPKEEHLPAD KTSTNSSNTI ISELATQEKS SSSGTTLKLI ALNIKSISDE
70 80 90 100 110 120
DVGYIQNVER LSLRKNHLTS LPASFKRLSR LQYLDLHNNN FKEIPYILTQ CPQLEILDLS
130 140 150 160 170 180
SNEIEALPDE ISSFWQDNIR VLSLKDNNVT SIRNLKSITK LNKLSILDLE DNKIPKEELD
190 200 210 220 230 240
QVQSYTPFHT GIPKEEYWAI AISRYLKDHP NLPTPEPKIS RAAKRMGFIN TNLSNGAMNE
250 260 270 280 290 300
NNIISLAPSA NTTISASTAM VSSNQTSATS FSGTVNAESE QSGAVNGTEL YNHTKYNDYF
310 320 330 340 350 360
KRLSILPEES MSNGHQKISH AELVVSCRKL LFSFTECQQA IRKIASFCKE KAVAVNVVSL
370 380 390 400 410 420
LYSVRSHTDN LVEVLQQTEN EDESHDQALI KLCLTIITNF KQIITLLRKN FEIFFKEDDL
430 440 450 460 470 480
CFIRMFYMTL MCAYMEMYNA WSFIKEDDQV SGSASKAPKK HSFSRHETSS SSITSGGGPA
490 500 510 520 530 540
ASTTSTHCSG NIKLLPKTRS TRTPSASALL SNSNILTGDT TAVPLLSPNL NGAHTHGPIL
550 560 570 580 590 600
GHQNAISNGS SQTNMNEVKT TSDTIPRQQL LQHNKSISDS KKESQAHEPK QHPVMTSSII
610 620 630 640 650 660
NASNSNNVSN VNITPPPMNG GGAANSSANV VETNIDIQLY QTLSTVVKMV SVVYNQLTSE
670 680 690 700 710 720
ISKIAIASTM GKQILTDSLA PKIRDLTETC RQAMDLSKQL NERLNVLIPN DSNSEKYLTS
730 740 750 760 770 780
LEKLKTWEIM NSFLKVIISI LANTKIVMSD VPNLNELRPN LANLAKITKD VTVILDLSSY
790
KAVSVSANSP E
References and
documentation are available.
Number of amino acids: 791
Molecular weight: 87325.91
Theoretical pI: 7.03
Total number of negatively charged residues (Asp + Glu): 79
Total number of positively charged residues (Arg + Lys): 78
Atomic composition:
Carbon C 3809
Hydrogen H 6177
Nitrogen N 1057
Oxygen O 1230
Sulfur S 27
Formula: C
3809H
6177N
1057O
1230S
27
Total number of atoms: 12300
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 47830
Abs 0.1% (=1 g/l) 0.548, assuming all pairs of Cys residues form cystines
Ext. coefficient 47330
Abs 0.1% (=1 g/l) 0.542, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 41.45
This classifies the protein as unstable.
Aliphatic index: 90.01
Grand average of hydropathicity (GRAVY): -0.344