ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVATVKRTIR IKTQQHILPE VPPVENFPVR QWSIEIVLLD DEGKEIPATI FDKVIYHLHP 

        70         80         90        100        110        120 
TFANPNRTFT DPPFRIEEQG WGGFPLDISV FLLEKAGERK IPHDLNFLQE SYEVEHVIQI 

       130        140        150        160        170        180 
PLNKPLLTEE LAKSGSTEET TANTGTIGKR RTTTNTTAEP KAKRAKTGSA STVKGSVDLE 

       190        200        210        220        230        240 
KLAFGLTKLN EDDLVGVVQM VTDNKTPEMN VTNNVEEGEF IIDLYSLPEG LLKSLWDYVK 


KNTE 

References and documentation are available.

Number of amino acids: 244

Molecular weight: 27440.22

Theoretical pI: 5.19

Amino acid composition: 
Ala (A)  11	  4.5%
Arg (R)   9	  3.7%
Asn (N)  13	  5.3%
Asp (D)  12	  4.9%
Cys (C)   0	  0.0%
Gln (Q)   7	  2.9%
Glu (E)  25	 10.2%
Gly (G)  14	  5.7%
His (H)   5	  2.0%
Ile (I)  16	  6.6%
Leu (L)  23	  9.4%
Lys (K)  19	  7.8%
Met (M)   3	  1.2%
Phe (F)  10	  4.1%
Pro (P)  16	  6.6%
Ser (S)  10	  4.1%
Thr (T)  25	 10.2%
Trp (W)   3	  1.2%
Tyr (Y)   4	  1.6%
Val (V)  19	  7.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 37
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	      1232
Hydrogen    H	      1959
Nitrogen    N	       323
Oxygen      O	       378
Sulfur      S	         3

Formula: C1232H1959N323O378S3
Total number of atoms: 3895

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    22460
Abs 0.1% (=1 g/l)   0.819

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.16
This classifies the protein as unstable.



Aliphatic index: 89.43

Grand average of hydropathicity (GRAVY): -0.418