Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVAYSPIIAT YGNRAEQFLE TDSDFAKYHA KLNKKLQHLR SRCHLVTKDT KKYSSKNKYG

70 80 90 100 110 120
EINSEDYDNK TKLIGVLILL HAERDLALAE TLKLRARQRG KLKKSEEKVL STRLKKACKT

130 140 150 160 170 180
ADKLVNVTQN EQQWITRAQY LAFAKLVHSE YLINGKRFKR KDNAKISNNL ALVFAALEHL

190 200 210 220 230 240
KNLSLLAEEV VDNIVNKYQY SLKQYAGNLI TTPEINNFIV ERVQSDENKD DELVKLLLDN

250 260 270 280 290 300
GFNMKKITTS TEDQKVTTNI NWRSFNAKII DAEVAQFLEQ GLSIHPTQIT QYTQRLSKLE

310 320 330 340 350 360
KALDRHEFFI ANHDDQDDID EMVENSSENN QIILAYIKYN ILLTSISRER DLFTHLWNQW

370 380 390 400 410 420
LKLNTSLPSK LTKYKEMERI VKNLTKYLSD IMELPGVYSD DELLSQLDLC KLYFQLFLNT

430 440 450 460 470 480
GCLSVLYQSK GRYMEALALY VDAYRRLENK LSEIESLDEI LLPANLLSLN SVRSLQKRIE

490 500 510 520 530 540
NGGNSVITLA EYEKRNHGGS LGKYDLTVIE KLDSKKILPT DIQLKNLFPL KPKMLPIPSK

550 560 570 580 590
PTLFDLAFNY ITYDKQEPSA SQVKDSVTET ESISQTPISN EQTEGEPKKK RGFLGLFGR


References and documentation are available.

Number of amino acids: 599 Molecular weight: 69006.04 Theoretical pI: 8.82
Amino acid composition: 
Ala (A) 33 5.5% Arg (R) 26 4.3% Asn (N) 41 6.8% Asp (D) 34 5.7% Cys (C) 4 0.7% Gln (Q) 28 4.7% Glu (E) 45 7.5% Gly (G) 20 3.3% His (H) 11 1.8% Ile (I) 38 6.3% Leu (L) 83 13.9% Lys (K) 61 10.2% Met (M) 7 1.2% Phe (F) 19 3.2% Pro (P) 15 2.5% Ser (S) 43 7.2% Thr (T) 35 5.8% Trp (W) 4 0.7% Tyr (Y) 26 4.3% Val (V) 26 4.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 79 Total number of positively charged residues (Arg + Lys): 87 Atomic composition: Carbon C 3088 Hydrogen H 4961 Nitrogen N 833 Oxygen O 931 Sulfur S 11 Formula: C3088H4961N833O931S11 Total number of atoms: 9824 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 60990 Abs 0.1% (=1 g/l) 0.884, assuming all pairs of Cys residues form cystines Ext. coefficient 60740 Abs 0.1% (=1 g/l) 0.880, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.60 This classifies the protein as stable. Aliphatic index: 96.88 Grand average of hydropathicity (GRAVY): -0.509