ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVCSVAATAS LLPSPPPKPT ALAADDHHAR LRAAAARSDL PAALAAFVAM SSAGAPPVLR 

        70         80         90        100        110        120 
TFTSLLKLCA ARGDLATGRA VHAQLAARGI DSEALAATAL ANMYAKCRRP ADARRVFDRM 

       130        140        150        160        170        180 
PVRDRVAWNA LVAGYARNGL ARMAMEMVVR MQEEEGERPD SITLVSVLPA CANARALAAC 

       190        200        210        220        230        240 
REAHAFAIRS GLEELVNVAT AILDAYCKCG DIRAARVVFD WMPTKNSVSW NAMIDGYAQN 

       250        260        270        280        290        300 
GDSREALALF NRMVEEGVDV TDVSVLAALQ ACGELGCLDE GMRVHELLVR IGLDSNVSVM 

       310        320        330        340        350        360 
NALITMYSKC KRVDLASHVF DELDRRTQVS WNAMILGCAQ NGCSEDAVRL FTRMQLENVK 

       370        380        390        400        410        420 
PDSFTLVSVI PALADISDPL QARWIHGYSI RLHLDQDVYV LTALIDMYAK CGRVNIARIL 

       430        440        450        460        470        480 
FNSARERHVI TWNAMIHGYG SHGFGKAAVE LFEEMKSIGI VPNETTFLSV LSACSHAGLV 

       490        500        510        520        530        540 
DEGREYFTSM KEDYGLEPGM EHYGTMVDLL GRAGKLDEAW AFIQKMPMDP GLSVYGAMLG 

       550        560        570        580        590        600 
ACKLHKNVEL AEESAQKIFE LGPQEGVYHV LLANIYANAS MWKDVARVRT AMEKNGLQKT 

       610        620        630        640        650        660 
PGWSIIQLKN EIHTFYSGST NHQQAKEIYS RLAKLIEEIK AVGYVPDTDS IHDVEDDVKA 

       670        680        690        700        710        720 
QLLNTHSEKL AIAFGLIRTA PGTTIQIKKN LRVCNDCHNA TKLISLVTGR EIIMRDIQRF 

       730 
HHFKDGKCSC GDYW 

References and documentation are available.

Number of amino acids: 734

Molecular weight: 80560.73

Theoretical pI: 6.44

Amino acid composition: 
Ala (A)  97	 13.2%
Arg (R)  48	  6.5%
Asn (N)  28	  3.8%
Asp (D)  43	  5.9%
Cys (C)  19	  2.6%
Gln (Q)  19	  2.6%
Glu (E)  42	  5.7%
Gly (G)  46	  6.3%
His (H)  22	  3.0%
Ile (I)  38	  5.2%
Leu (L)  71	  9.7%
Lys (K)  31	  4.2%
Met (M)  28	  3.8%
Phe (F)  20	  2.7%
Pro (P)  24	  3.3%
Ser (S)  43	  5.9%
Thr (T)  31	  4.2%
Trp (W)  10	  1.4%
Tyr (Y)  19	  2.6%
Val (V)  55	  7.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 85
Total number of positively charged residues (Arg + Lys): 79

Atomic composition:

Carbon      C	      3538
Hydrogen    H	      5648
Nitrogen    N	      1010
Oxygen      O	      1045
Sulfur      S	        47

Formula: C3538H5648N1010O1045S47
Total number of atoms: 11288

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    84435
Abs 0.1% (=1 g/l)   1.048, assuming all pairs of Cys residues form cystines


Ext. coefficient    83310
Abs 0.1% (=1 g/l)   1.034, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.11
This classifies the protein as stable.



Aliphatic index: 92.86

Grand average of hydropathicity (GRAVY): -0.017