ProtParam
User-provided sequence:
10 20 30 40 50 60
MVDKNRTLHE LSSKNFSRTP NGLIFTNDLK TVYSIFLICL DLKEKKHSSD TKSFLLTAFT
70 80 90 100 110 120
KHFHFTFTYQ EAIKAMGQLE LKVDMNTTCI NVSYNIKPSL ARHLLTLFMS SKLLHTPQDR
130 140 150 160 170 180
TRGEPKEKVL FQPTPKGVAV LQKYVRDIGL KTMPDILLSS FNSMKLFTFE RSSVTDSIIH
190 200 210 220 230 240
SDYLIHILFI KMMGAKPNVW SPTNADDPLP CLSSLLEYTN NDDTFTFEKS KPEQGWQAQI
250 260 270 280 290 300
GNIDINDLER VSPLAHRFFT NPDSESHTQY YVSNAGIRLF ENKTFGTSKK IVIKYTFTTK
310 320 330 340 350 360
AIWQWIMDCT DIMHVKEAVS LAALFLKTGL IVPVLLQPSR TDKKKFQISR SSFFTLSKRG
370 380 390 400 410 420
WDLVSWTGCK SNNIRAPNGS TIDLDFTLRG HMTVRDEKKT LDDSEGFSQD MLISSSNLNK
430 440 450 460 470 480
LDYVLTDPGM RYLFRRHLEK ELCVENLDVF IEIKRFLKKM TILKKLIDSK HCDKKSNTST
490 500 510 520 530 540
SKNNIVKTID SALMKQANEC LEMAYHIYSS YIMIGSPYQL NIHHNLRQNI SDIMLHPHSP
550 560 570 580 590 600
LSEHFPTNLY DPSPASAESA ASSISSTEAD TLGEPPEVSL KPSKNLSNEN CSFKKQGFKH
610 620 630 640 650 660
QLKEYKPAPL TLAETHSPNA SVENSHTIVR YGMDNTQNDT KSVESFPATL KVLRKLYPLF
670 680 690
EIVSNEMYRL MNNDSFQKFT QSDVYKDASA LIEIQEKC
References and
documentation are available.
Number of amino acids: 698
Molecular weight: 79716.36
Theoretical pI: 8.75
Total number of negatively charged residues (Asp + Glu): 77
Total number of positively charged residues (Arg + Lys): 86
Atomic composition:
Carbon C 3564
Hydrogen H 5615
Nitrogen N 947
Oxygen O 1062
Sulfur S 31
Formula: C
3564H
5615N
947O
1062S
31
Total number of atoms: 11219
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 64915
Abs 0.1% (=1 g/l) 0.814, assuming all pairs of Cys residues form cystines
Ext. coefficient 64290
Abs 0.1% (=1 g/l) 0.806, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 39.77
This classifies the protein as stable.
Aliphatic index: 81.99
Grand average of hydropathicity (GRAVY): -0.399