ProtParam
User-provided sequence:
10 20 30 40 50 60
MVDPTIHNTT TYLEEIAKGN GQTEFEILIL KGLELIHVGK GILRCKLLVT DHVVGEDGSW
70 80 90 100 110 120
NAGVITAVMD SIGASAVYSS GGGLHISVDL NSSFYSTAKI HETVEIEARV NGSNGGLKSA
130 140 150
VIEIRRETSG EIIATGRLWM APLSVKAIQN VSTLSKL
References and
documentation are available.
Number of amino acids: 157
Molecular weight: 16704.11
Theoretical pI: 5.70
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 13
Atomic composition:
Carbon C 737
Hydrogen H 1203
Nitrogen N 201
Oxygen O 231
Sulfur S 4
Formula: C
737H
1203N
201O
231S
4
Total number of atoms: 2376
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 0.926, assuming all pairs of Cys residues form cystines
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 0.926, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 39.74
This classifies the protein as stable.
Aliphatic index: 109.87
Grand average of hydropathicity (GRAVY): 0.157