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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE

70 80 90 100 110 120
TEPKDDNLPI KRERQGNVAS LVQRISTYGL PAGGIQPHPQ TKAIKKKTKK RQCKVLFDYS

130 140 150 160 170 180
PQNEDELELI VGDVIDVIEE VEEGWWSGTL NNKLGLFPSN FVKELESTED GETHNAQEES

190 200 210 220 230 240
EVPLTGPTSP LPSPGNGSEP APGSVAQPKK IRGIGFGDIF KEGSVKLRTR TSSSETEEKK

250 260 270 280 290 300
TEKPLILQPL GSRTQNVEVT KPDVDGKIKA KEYCRTLFPY TGTNEDELTF REGEIIHLIS

310 320 330 340 350 360
KETGEAGWWK GELNGKEGVF PDNFAVQISE LDKDFPKPKK PPPPAKGPAP KPDLSAAEKK

370 380 390 400 410 420
AFPLKAEEKD EKSLLEQKPS KPAAPQVPPK KPTAPTKASN LLRSPGAVYP KRPEKPVPPP

430 440 450 460 470 480
PPAAKINGEV SIISSKIDTE PVSKPKLDPE QLPVRPKSVD LDAFVARNSK ETDDVNFDDI

490 500 510 520 530 540
ASSENLLHLT ANRPKMPGRR LPGRFNGGHS PTQSPEKTLK LPKEDDSGNL KPLEFKKDAS

550 560 570 580 590 600
YSSKPSLSTP SSASKVNTAA FLTPLELKAK AEADDGKKNS VDELRAQIIE LLCIVDALKK

610 620 630
DHGKELEKLR KELEEEKAMR SNLEVEIAKL KKAVLLS


References and documentation are available.

Number of amino acids: 637 Molecular weight: 70431.95 Theoretical pI: 6.07
Amino acid composition: 
Ala (A) 39 6.1% Arg (R) 26 4.1% Asn (N) 26 4.1% Asp (D) 38 6.0% Cys (C) 3 0.5% Gln (Q) 17 2.7% Glu (E) 68 10.7% Gly (G) 41 6.4% His (H) 7 1.1% Ile (I) 30 4.7% Leu (L) 57 8.9% Lys (K) 75 11.8% Met (M) 4 0.6% Phe (F) 18 2.8% Pro (P) 62 9.7% Ser (S) 45 7.1% Thr (T) 31 4.9% Trp (W) 5 0.8% Tyr (Y) 9 1.4% Val (V) 36 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 106 Total number of positively charged residues (Arg + Lys): 101 Atomic composition: Carbon C 3126 Hydrogen H 5040 Nitrogen N 852 Oxygen O 978 Sulfur S 7 Formula: C3126H5040N852O978S7 Total number of atoms: 10003 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41035 Abs 0.1% (=1 g/l) 0.583, assuming all pairs of Cys residues form cystines Ext. coefficient 40910 Abs 0.1% (=1 g/l) 0.581, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.13 This classifies the protein as unstable. Aliphatic index: 75.78 Grand average of hydropathicity (GRAVY): -0.792