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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVEGWRNGFR DATNSKPLFV TIYATVIIGV LVSSFYVFSA IYSPTNGSSS FLSFPPLSTS

70 80 90 100 110 120
GRIHSLPQEN ATLELPVAPP PPPQALPPPV LEEAQGNSLG KIWVSPPRDK KMPPLETFKL

130 140 150 160 170 180
TKELFGERVK DNVIIVTFGN YAFMDFILTW VKHLTDLDLS NILVGAMDTK LLEALYWKGV

190 200 210 220 230 240
PVFDMGSHMS TVDVGWGSPT FHKMGREKVI LIDSVLPFGY ELLMCDTDMV WLKNPMPYLA

250 260 270 280 290 300
RFPDADVLTS SDQVVPTVID DSLDIWQQVG AAYNIGIFHW RPTESAKKLA KEWKEILLAD

310 320 330 340 350 360
DKVWDQNGFN EIVRRQLGPS VEGDSGLFYA YDGNLKVGIL PASIFCSGHT YFVQAMYQQL

370 380 390 400 410 420
RLEPYAVHTT FQYAGTEGKR HRLREGMVFY DPPEYYDSPG GFIAFKPSIP KSLLLDGKHT

430 440 450 460 470 480
IESHFILVNH QMKQIRSALA IASLLNRTLV MPPIWCRLDR LWFGHPGTLQ GSMTRQPFIC

490 500 510 520 530 540
PLDHVFEVNI MLKELPEEEF GPGIGIREYS FLDNPLLPKQ VKESWLDVQL CQEGKEGCEA

550 560 570 580 590 600
SNNTSPSRVL KFPKRSNEDT FKAIFSSFDD VKVIKFSSIE DAFIGFSDKE REERFRRRVK

610 620 630 640
RYVGIWCCEE NKTPGHIYYD MYWDEKPGWK PVPPQTPEED HPPL


References and documentation are available.

Number of amino acids: 644 Molecular weight: 73213.08 Theoretical pI: 5.69
Amino acid composition: 
Ala (A) 29 4.5% Arg (R) 28 4.3% Asn (N) 21 3.3% Asp (D) 38 5.9% Cys (C) 8 1.2% Gln (Q) 20 3.1% Glu (E) 41 6.4% Gly (G) 43 6.7% His (H) 15 2.3% Ile (I) 37 5.7% Leu (L) 60 9.3% Lys (K) 38 5.9% Met (M) 17 2.6% Phe (F) 38 5.9% Pro (P) 53 8.2% Ser (S) 45 7.0% Thr (T) 30 4.7% Trp (W) 16 2.5% Tyr (Y) 22 3.4% Val (V) 45 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 79 Total number of positively charged residues (Arg + Lys): 66 Atomic composition: Carbon C 3352 Hydrogen H 5107 Nitrogen N 853 Oxygen O 941 Sulfur S 25 Formula: C3352H5107N853O941S25 Total number of atoms: 10278 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 121280 Abs 0.1% (=1 g/l) 1.657, assuming all pairs of Cys residues form cystines Ext. coefficient 120780 Abs 0.1% (=1 g/l) 1.650, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.90 This classifies the protein as unstable. Aliphatic index: 83.51 Grand average of hydropathicity (GRAVY): -0.233