ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVEQTQHPTI LQKVSGQLLS SSVSQDIRGY ASASKRPATY QKHAAYGNYS NAAFQYPLVA 

        70         80         90        100        110        120 
ASQIATTTSP VFVQAPGEKG FTNFAIDFMM GGVSAAVSKT AAAPIERVKL LIQNQDEMLK 

       130        140        150        160        170        180 
AGRLTEPYKG IRDCFGRTIR DEGIGSLWRG NTANVIRYFP TQALNFAFKD YFKRLFNFKK 

       190        200        210        220        230        240 
DKDGYWKWFA GNLASGGAAG ASSLLFVYSL DYARTRLAND SKSAKKGGGE RQFNGLVDVY 

       250        260        270        280        290        300 
KKTLKSDGIA GLYRGFNISC AGIIVYRGLY FGLYDSVKPV LLTGDLQDSF FASFALGWLI 

       310        320        330        340        350        360 
TNGAGLASYP IDTVRRRMMM TSGEAVKYKS SFDAFSQIVK KEGAKSLFKG AGANILRAVA 

       370        380 
GAGVLAGYDK LQLIVFGKKY GSGGA 

References and documentation are available.

Number of amino acids: 385

Molecular weight: 41745.81

Theoretical pI: 9.79

Amino acid composition: 
Ala (A)  45	 11.7%
Arg (R)  19	  4.9%
Asn (N)  14	  3.6%
Asp (D)  18	  4.7%
Cys (C)   2	  0.5%
Gln (Q)  16	  4.2%
Glu (E)   9	  2.3%
Gly (G)  43	 11.2%
His (H)   2	  0.5%
Ile (I)  19	  4.9%
Leu (L)  32	  8.3%
Lys (K)  30	  7.8%
Met (M)   7	  1.8%
Phe (F)  24	  6.2%
Pro (P)  10	  2.6%
Ser (S)  31	  8.1%
Thr (T)  18	  4.7%
Trp (W)   4	  1.0%
Tyr (Y)  20	  5.2%
Val (V)  22	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 27
Total number of positively charged residues (Arg + Lys): 49

Atomic composition:

Carbon      C	      1892
Hydrogen    H	      2942
Nitrogen    N	       510
Oxygen      O	       539
Sulfur      S	         9

Formula: C1892H2942N510O539S9
Total number of atoms: 5892

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    51925
Abs 0.1% (=1 g/l)   1.244, assuming all pairs of Cys residues form cystines


Ext. coefficient    51800
Abs 0.1% (=1 g/l)   1.241, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 23.70
This classifies the protein as stable.



Aliphatic index: 79.92

Grand average of hydropathicity (GRAVY): -0.111