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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVFSYEHYMN LIYHLDDANE TVPSDIAKRV VSNAMAPVIT VTSTVLLDRH IEETYGIDSL

70 80 90 100 110 120
YMLLRFFGGC VSDRDQANEV KLGTDGLKVT EEGVENEKDG TNGLTVPRQT RVRSNSNSLY

130 140 150 160 170 180
QRDATQSQYV RFTKPLADLI NTQDANDMLF DYHSLEVYLQ EYLSVVDKKF SPHIPHHLLK

190 200 210 220 230 240
TSIYHSFFAL AISSTSKLSP FECFNHPIVS LLAIDITRNE DYETAAEQLK EFKSMNNNIP

250 260 270 280 290 300
SFPSFINTND ILPVFLLCYN KDNETEFEEC QTLAGKLKKQ LFVESIILPL WSTEFTDNLV

310 320 330 340 350 360
VSLHQPVMSS IEEIMFFLQN PVDHKLPLKL VNCIYDQIDM IVYDLMKPFM KRKMTFWEET

370 380 390 400 410 420
ILTPRKSLFH GAKFFKKFMN KSTQALSQPN SLLKENHGSN YLSSTSPEFL MRKLADWSMM

430 440 450 460 470 480
VSDFKTAYTT YESLCQDFER MPKYLASCSE WCAVSLLMGA QNIVTAKMLK NEINPAIERA

490 500 510 520 530 540
LGAYELCATE SNAHRKFGDS DDLSAPVRSY ETRCMFLASE LFLSLSDTWT STPFAIAYLE

550 560 570 580 590 600
TILNECKLGP LSEIMIWERL SDCYGMRIDP RIKHRIGNLE LLQKKEENMD DPKNADVFTT

610 620 630 640 650 660
EDILSKGLTR NRKAALFKLI AARKWCEQKQ WRELSWCLDD LESTYSDLKC FNKENLLYTR

670
LRNELIAARQ DM


References and documentation are available.

Number of amino acids: 672 Molecular weight: 77509.73 Theoretical pI: 5.43
Amino acid composition: 
Ala (A) 38 5.7% Arg (R) 29 4.3% Asn (N) 38 5.7% Asp (D) 41 6.1% Cys (C) 15 2.2% Gln (Q) 21 3.1% Glu (E) 50 7.4% Gly (G) 18 2.7% His (H) 15 2.2% Ile (I) 36 5.4% Leu (L) 79 11.8% Lys (K) 44 6.5% Met (M) 24 3.6% Phe (F) 35 5.2% Pro (P) 26 3.9% Ser (S) 56 8.3% Thr (T) 42 6.2% Trp (W) 9 1.3% Tyr (Y) 25 3.7% Val (V) 31 4.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 91 Total number of positively charged residues (Arg + Lys): 73 Atomic composition: Carbon C 3464 Hydrogen H 5399 Nitrogen N 901 Oxygen O 1037 Sulfur S 39 Formula: C3464H5399N901O1037S39 Total number of atoms: 10840 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 87625 Abs 0.1% (=1 g/l) 1.131, assuming all pairs of Cys residues form cystines Ext. coefficient 86750 Abs 0.1% (=1 g/l) 1.119, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.24 This classifies the protein as unstable. Aliphatic index: 85.77 Grand average of hydropathicity (GRAVY): -0.293