ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVGGFRVIHL VRPFLAFLPE VQSPERKIPF REKVIYTVIS LFIFLVCSQL PLYGIHSTTG 

        70         80         90        100        110        120 
ADPFYWMRVI LASSRGTVME LGITPIVTSG MVMQLLAGSK IIEIDNNVRE DRALLNGAQK 

       130        140        150        160        170        180 
LLGILIAVGQ AVAYVLSGMY GSVGELGVGN AILIIVQLCF AAIIVLCLDE LLQKGYGLGS 

       190        200        210        220        230        240 
GISLFIATNI CESIIWKAFS PTTINSGRGA QFEGAVIALF HLLITRTDKV RALREAFFRQ 

       250        260        270        280        290        300 
NLPNVTNLHA TVLIFLIVIY FQGFRVVLPV RSKNARGQRG SYPIKLFYTS NMPIILQSAL 

       310        320        330        340        350        360 
VSNIYFISQI LYRKFGGNFL VNLIGTWKES EYSGQSIPVG GIAYYITAPS SLAEMATHPF 

       370        380        390        400        410        420 
HALFYLVFML AACALFSKTW IEVSGSSAKD VARQLREQQM VMPGHRDSNL QKELNRYIPT 

       430        440        450        460        470 
AAAFGGLCIG ALTVLADLMG AIGSGTGILL AVTIIYQYFE TFEKEKASEL GFFGL 

References and documentation are available.

Number of amino acids: 475

Molecular weight: 52131.37

Theoretical pI: 9.17

Amino acid composition: 
Ala (A)  40	  8.4%
Arg (R)  22	  4.6%
Asn (N)  16	  3.4%
Asp (D)   8	  1.7%
Cys (C)   6	  1.3%
Gln (Q)  19	  4.0%
Glu (E)  21	  4.4%
Gly (G)  43	  9.1%
His (H)   7	  1.5%
Ile (I)  47	  9.9%
Leu (L)  57	 12.0%
Lys (K)  16	  3.4%
Met (M)  12	  2.5%
Phe (F)  30	  6.3%
Pro (P)  17	  3.6%
Ser (S)  33	  6.9%
Thr (T)  23	  4.8%
Trp (W)   4	  0.8%
Tyr (Y)  18	  3.8%
Val (V)  36	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 29
Total number of positively charged residues (Arg + Lys): 38

Atomic composition:

Carbon      C	      2406
Hydrogen    H	      3794
Nitrogen    N	       610
Oxygen      O	       643
Sulfur      S	        18

Formula: C2406H3794N610O643S18
Total number of atoms: 7471

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    49195
Abs 0.1% (=1 g/l)   0.944, assuming all pairs of Cys residues form cystines


Ext. coefficient    48820
Abs 0.1% (=1 g/l)   0.936, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.14
This classifies the protein as stable.



Aliphatic index: 115.79

Grand average of hydropathicity (GRAVY): 0.529