ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVHNKVTIIG SGPAAHTAAI YLARAEIKPI LYEGMMANGI AAGGQLTTTT EIENFPGFPD 

        70         80         90        100        110        120 
GLTGSELMDR MREQSTKFGT EIITETVSKV DLSSKPFKLW TEFNEDAEPV TTDAIILATG 

       130        140        150        160        170        180 
ASAKRMHLPG EETYWQKGIS ACAVCDGAVP IFRNKPLAVI GGGDSACEEA QFLTKYGSKV 

       190        200        210        220        230        240 
FMLVRKDHLR ASTIMQKRAE KNEKIEILYN TVALEAKGDG KLLNALRIKN TKKNEETDLP 

       250        260        270        280        290        300 
VSGLFYAIGH TPATKIVAGQ VDTDEAGYIK TVPGSSLTSV PGFFAAGDVQ DSKYRQAITS 

       310 
AGSGCMAALD AEKYLTSLE 

References and documentation are available.

Number of amino acids: 319

Molecular weight: 34238.07

Theoretical pI: 5.67

Amino acid composition: 
Ala (A)  36	 11.3%
Arg (R)  10	  3.1%
Asn (N)  10	  3.1%
Asp (D)  15	  4.7%
Cys (C)   4	  1.3%
Gln (Q)   8	  2.5%
Glu (E)  24	  7.5%
Gly (G)  29	  9.1%
His (H)   5	  1.6%
Ile (I)  22	  6.9%
Leu (L)  24	  7.5%
Lys (K)  24	  7.5%
Met (M)   9	  2.8%
Phe (F)  11	  3.4%
Pro (P)  13	  4.1%
Ser (S)  19	  6.0%
Thr (T)  28	  8.8%
Trp (W)   2	  0.6%
Tyr (Y)   9	  2.8%
Val (V)  17	  5.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 34

Atomic composition:

Carbon      C	      1514
Hydrogen    H	      2421
Nitrogen    N	       403
Oxygen      O	       472
Sulfur      S	        13

Formula: C1514H2421N403O472S13
Total number of atoms: 4823

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    24660
Abs 0.1% (=1 g/l)   0.720, assuming all pairs of Cys residues form cystines


Ext. coefficient    24410
Abs 0.1% (=1 g/l)   0.713, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.80
This classifies the protein as stable.



Aliphatic index: 82.98

Grand average of hydropathicity (GRAVY): -0.158