ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVHVSSSHGA KDGSEEAYDY RGNPPDKSKT GGWLGAGLIL GSELSERICV MGISMNLVTY 

        70         80         90        100        110        120 
LVGDLHISSA KSATIVTNFM GTLNLLGLLG GFLADAKLGR YKMVAISASV TALGVLLLTV 

       130        140        150        160        170        180 
ATTISSMRPP ICDDFRRLHH QCIEANGHQL ALLYVALYTI ALGGGGIKSN VSGFGSDQFD 

       190        200        210        220        230        240 
TSDPKEEKQM IFFFNRFYFS ISVGSLFAVI ALVYVQDNVG RGWGYGISAA TMVVAAIVLL 

       250        260        270        280        290        300 
CGTKRYRFKK PKGSPFTTIW RVGFLAWKKR KESYPAHPSL LNGYDNTTVP HTEMLKCLDK 

       310        320        330        340        350        360 
AAISKNESSP SSKDFEEKDP WIVSTVTQVE EVKLVMKLVP IWATNILFWT IYSQMTTFTV 

       370        380        390        400        410        420 
EQATFMDRKL GSFTVPAGSY SAFLILTILL FTSLNERVFV PLTRRLTKKP QGITSLQRIG 

       430        440        450        460        470        480 
VGLVFSMAAM AVAAVIENAR REAAVNNDKK ISAFWLVPQY FLVGAGEAFA YVGQLEFFIR 

       490        500        510        520        530        540 
EAPERMKSMS TGLFLSTISM GFFVSSLLVS LVDRVTDKSW LRSNLNKARL NYFYWLLVVL 

       550        560        570        580        590 
GALNFLIFIV FAMKHQYKAD VITVVVTDDD SVEKEVTKKE SSEFELKDIP 

References and documentation are available.

Number of amino acids: 590

Molecular weight: 65245.86

Theoretical pI: 9.10

Amino acid composition: 
Ala (A)  46	  7.8%
Arg (R)  24	  4.1%
Asn (N)  20	  3.4%
Asp (D)  24	  4.1%
Cys (C)   5	  0.8%
Gln (Q)  13	  2.2%
Glu (E)  27	  4.6%
Gly (G)  43	  7.3%
His (H)   9	  1.5%
Ile (I)  34	  5.8%
Leu (L)  63	 10.7%
Lys (K)  37	  6.3%
Met (M)  18	  3.1%
Phe (F)  36	  6.1%
Pro (P)  19	  3.2%
Ser (S)  52	  8.8%
Thr (T)  38	  6.4%
Trp (W)  10	  1.7%
Tyr (Y)  19	  3.2%
Val (V)  53	  9.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 61

Atomic composition:

Carbon      C	      2980
Hydrogen    H	      4674
Nitrogen    N	       760
Oxygen      O	       835
Sulfur      S	        23

Formula: C2980H4674N760O835S23
Total number of atoms: 9272

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    83560
Abs 0.1% (=1 g/l)   1.281, assuming all pairs of Cys residues form cystines


Ext. coefficient    83310
Abs 0.1% (=1 g/l)   1.277, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 29.35
This classifies the protein as stable.



Aliphatic index: 97.97

Grand average of hydropathicity (GRAVY): 0.205