ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVIILLGLCT LGFPRTAFCP SIMTNSTVSI NTPPPYLTLA CNEKLPTVMS IAGSDSSGGA 

        70         80         90        100        110        120 
GVEADIKTIT AHRCYAMTCV TTLTAQTPVK VYGAHNIPKK MVSQILDANL QDMKCNVIKT 

       130        140        150        160        170        180 
GMLTVDAIEV LHEKLLQLGE NRPKLVIDPV LCAASDSSPT GKDVVSLIIE KISPFADILT 

       190        200        210        220        230        240 
PNISDCFMLL GENREVSKLQ DVLEIAKDLS RITNCSNILV KGGHIPCDDG KEKHITDVLY 

       250        260        270        280        290        300 
LGAEQKFITF KGQFVNTTRT HGAGCTLASA IASNLARGYS LSQSVYGGIE YVQNAIAIGC 

       310        320        330        340        350        360 
DVTKKAVKVG PINHVYAVEI PLEKMLTDEC FTASDAVPKK PIEGSLDKIP GGSFFNYLIN 

       370        380        390        400        410        420 
HPKVKPHWDA YVNHEFVKRV ADGTLERKKF QFFIEQDYLY LIDYVRVCCV TGSKSPTLED 

       430        440        450        460        470        480 
LEKDLVIADC ARNELNEHER RLREEFGVKD PDYLQKIKRG PALRAYCRYL IDISRRGNWQ 

       490        500        510        520        530        540 
EIVVALNPCL MGYVYAVDKV KDKITAAEGS IYSEWCDTCA SSFCYQAVLE GERLMNHILE 

       550        560        570 
TYPPDQLDSL VTIFARGCEL ETNFWTAAME YE 

References and documentation are available.

Number of amino acids: 572

Molecular weight: 63307.04

Theoretical pI: 5.66

Amino acid composition: 
Ala (A)  42	  7.3%
Arg (R)  21	  3.7%
Asn (N)  24	  4.2%
Asp (D)  34	  5.9%
Cys (C)  22	  3.8%
Gln (Q)  15	  2.6%
Glu (E)  36	  6.3%
Gly (G)  35	  6.1%
His (H)  12	  2.1%
Ile (I)  43	  7.5%
Leu (L)  53	  9.3%
Lys (K)  38	  6.6%
Met (M)  12	  2.1%
Phe (F)  18	  3.1%
Pro (P)  27	  4.7%
Ser (S)  33	  5.8%
Thr (T)  37	  6.5%
Trp (W)   4	  0.7%
Tyr (Y)  22	  3.8%
Val (V)  44	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 70
Total number of positively charged residues (Arg + Lys): 59

Atomic composition:

Carbon      C	      2817
Hydrogen    H	      4478
Nitrogen    N	       740
Oxygen      O	       844
Sulfur      S	        34

Formula: C2817H4478N740O844S34
Total number of atoms: 8913

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    56155
Abs 0.1% (=1 g/l)   0.887, assuming all pairs of Cys residues form cystines


Ext. coefficient    54780
Abs 0.1% (=1 g/l)   0.865, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.77
This classifies the protein as stable.



Aliphatic index: 95.10

Grand average of hydropathicity (GRAVY): -0.036