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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVITSKPCVF LDRDGVIVVP EFRNGRTFAP KTLEGFSYFP DTKKTLVRLK TAGYLLIVVT

70 80 90 100 110 120
NQPDVGNGIT SLATIENMHN KMRQELPIDH IEVCYHSQKD NCHCRKPKAG MLLNSLKKFN

130 140 150 160 170 180
IIVQKSFMIG DRSSDIEAGR KLNLKTIFID HHYQEPITAN PDYICQDLSQ GVEIILREEN


A


References and documentation are available.

Number of amino acids: 181 Molecular weight: 20563.80 Theoretical pI: 8.25
Amino acid composition: 
Ala (A) 7 3.9% Arg (R) 9 5.0% Asn (N) 11 6.1% Asp (D) 11 6.1% Cys (C) 5 2.8% Gln (Q) 7 3.9% Glu (E) 10 5.5% Gly (G) 10 5.5% His (H) 6 3.3% Ile (I) 17 9.4% Leu (L) 15 8.3% Lys (K) 14 7.7% Met (M) 5 2.8% Phe (F) 8 4.4% Pro (P) 9 5.0% Ser (S) 9 5.0% Thr (T) 11 6.1% Trp (W) 0 0.0% Tyr (Y) 5 2.8% Val (V) 12 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 21 Total number of positively charged residues (Arg + Lys): 23 Atomic composition: Carbon C 913 Hydrogen H 1464 Nitrogen N 252 Oxygen O 267 Sulfur S 10 Formula: C913H1464N252O267S10 Total number of atoms: 2906 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 7700 Abs 0.1% (=1 g/l) 0.374, assuming all pairs of Cys residues form cystines Ext. coefficient 7450 Abs 0.1% (=1 g/l) 0.362, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.89 This classifies the protein as unstable. Aliphatic index: 92.04 Grand average of hydropathicity (GRAVY): -0.275