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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVKETEYYDI LGIKPEATPT EIKKAYRRKA METHPDKHPD DPDAQAKFQA VGEAYQVLSD

70 80 90 100 110 120
PGLRSKYDQF GKEDAVPQQG FEDASEYFTA IFGGDGFKDW IGEFSLFKEL NEATEMFGKE

130 140 150 160 170 180
DEEGTAATET EKADESTDGG MVKHDTNKAE SLKKDKLSKE QREKLMEMEK KRREDMMKQV

190 200 210 220 230 240
DELAEKLNEK ISRYLIAVKS NNLEEFTRKL DQEIEDLKLE SFGLELLYLL ARVYKTKANN

250 260 270 280 290 300
FIMSKKTYGI SKIFTGTRDN ARSVKSAYNL LSTGLEAQKA MEKMSEVNTD ELDQYERAKF

310 320 330 340 350 360
ESTMAGKALG VMWAMSKFEL ERKLKDVCNK ILNDKKVPSK ERIAKAKAML FIAHKFASAR

370 380 390
RSPEEAEEAR VFEELILGEQ EKEHKKHTVA R


References and documentation are available.

Number of amino acids: 391 Molecular weight: 44854.89 Theoretical pI: 5.63
Amino acid composition: 
Ala (A) 36 9.2% Arg (R) 18 4.6% Asn (N) 12 3.1% Asp (D) 25 6.4% Cys (C) 1 0.3% Gln (Q) 12 3.1% Glu (E) 52 13.3% Gly (G) 20 5.1% His (H) 6 1.5% Ile (I) 15 3.8% Leu (L) 31 7.9% Lys (K) 51 13.0% Met (M) 15 3.8% Phe (F) 18 4.6% Pro (P) 9 2.3% Ser (S) 21 5.4% Thr (T) 20 5.1% Trp (W) 2 0.5% Tyr (Y) 12 3.1% Val (V) 15 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 77 Total number of positively charged residues (Arg + Lys): 69 Atomic composition: Carbon C 1975 Hydrogen H 3148 Nitrogen N 534 Oxygen O 623 Sulfur S 16 Formula: C1975H3148N534O623S16 Total number of atoms: 6296 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28880 Abs 0.1% (=1 g/l) 0.644, assuming all pairs of Cys residues form cystines Ext. coefficient 28880 Abs 0.1% (=1 g/l) 0.644, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.68 This classifies the protein as stable. Aliphatic index: 66.21 Grand average of hydropathicity (GRAVY): -0.841