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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVKGPGLYTE IGKKARDLLY KDHNSDQKFS ITTFSPAGVA ITSTGTKKGD LLLGDVAFQS

70 80 90 100 110 120
RRKNITTDLK VCTDSTFLIT ATVDEAAPGL RSIFSFKVPD QNSGKVELQY LHEYAGISTS

130 140 150 160 170 180
MGLTQNPTVN FSGVIGSNVL AVGTDVSFDT KSGNFTKINA GLSFTKEDLI ASLTVNDKGD

190 200 210 220 230 240
LLNASYYHIV NPLFNTAVGA EVSHKLSSKD STITVGTQHS LDPLTSVKAR VNSAGIASAL

250 260 270
IQHEWKPKSF FTISGEVDTK SIDKSAKVGL ALALKP


References and documentation are available.

Number of amino acids: 276 Molecular weight: 29425.36 Theoretical pI: 8.77
Amino acid composition: 
Ala (A) 21 7.6% Arg (R) 5 1.8% Asn (N) 13 4.7% Asp (D) 18 6.5% Cys (C) 1 0.4% Gln (Q) 7 2.5% Glu (E) 8 2.9% Gly (G) 22 8.0% His (H) 6 2.2% Ile (I) 16 5.8% Leu (L) 26 9.4% Lys (K) 24 8.7% Met (M) 2 0.7% Phe (F) 13 4.7% Pro (P) 9 3.3% Ser (S) 30 10.9% Thr (T) 27 9.8% Trp (W) 1 0.4% Tyr (Y) 6 2.2% Val (V) 21 7.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 26 Total number of positively charged residues (Arg + Lys): 29 Atomic composition: Carbon C 1311 Hydrogen H 2100 Nitrogen N 348 Oxygen O 412 Sulfur S 3 Formula: C1311H2100N348O412S3 Total number of atoms: 4174 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.491, assuming all pairs of Cys residues form cystines Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.491, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 18.93 This classifies the protein as stable. Aliphatic index: 89.02 Grand average of hydropathicity (GRAVY): -0.114