ProtParam
User-provided sequence:
10 20 30 40 50 60
MVKSTSKTST KETVTKQPTE EKPIQEKEEL ALETSSSSSD EEDEKDEDEI EGLAASDDEQ
70 80 90 100 110 120
SGTHKIKRLN PKKQANEKKS KDKKTLEEYS GIIYVSRLPH GFHEKELSKY FAQFGDLKEV
130 140 150 160 170 180
RLARNKKTGN SRHYGFLEFV NKEDAMIAQE SMNNYLLMGH LLQVRVLPKG AKIEKLYKYK
190 200 210 220
KRVLVEKGIT KPVKQLKDNM KQKHEERIKK LAKSGIEFKW
References and
documentation are available.
Number of amino acids: 220
Molecular weight: 25447.07
Theoretical pI: 9.26
Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 46
Atomic composition:
Carbon C 1123
Hydrogen H 1830
Nitrogen N 312
Oxygen O 349
Sulfur S 5
Formula: C
1123H
1830N
312O
349S
5
Total number of atoms: 3619
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 15930
Abs 0.1% (=1 g/l) 0.626
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 46.76
This classifies the protein as unstable.
Aliphatic index: 69.14
Grand average of hydropathicity (GRAVY): -1.080