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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVKTEICGKG SSQGSEEERL SQLPDHLICV ILSHLSTKDA VRTSILSTRW RNLWQLVPVL

70 80 90 100 110 120
DFDSRELRSF SEFVSFAGSF FYLHKDSYIQ KLRVCIYDLA GNYYLTSWID LVTRHRIQHI

130 140 150 160 170 180
DISVFTCSGF GVIPLSLYTC DTLVHLKLSR VTMVNVEFVS LPCLKILDLD FVNFTNETTL

190 200 210 220 230 240
DKIISCSPVL EELTIVKSSE DNVKIIQVRS QTLKRVEIHR RFDRHNGLVI DTPLLQFLSI

250 260 270 280 290 300
KAHSIKSIEF INLGFTTKVD IDVNLLDPND LSNRSMTRDF FTTISRVRSL VIRHGTIKDI

310 320 330 340 350 360
FHYMELEPLQ QFCYLSELSA VCSISNLEML LNLLKSCPKL ESLSLKLVDY EKNKKEEVMS

370 380 390 400 410 420
STVPPPCLVS SLKFVKLESQ LLGCGTELKV ARYFLENSTI LEKLTLKIDY MYKDEANVNH

430 440
IRQTLHAVPR CSSTCEVVIH SLLY


References and documentation are available.

Number of amino acids: 444 Molecular weight: 50907.18 Theoretical pI: 6.91
Amino acid composition: 
Ala (A) 8 1.8% Arg (R) 23 5.2% Asn (N) 17 3.8% Asp (D) 24 5.4% Cys (C) 14 3.2% Gln (Q) 12 2.7% Glu (E) 27 6.1% Gly (G) 12 2.7% His (H) 14 3.2% Ile (I) 33 7.4% Leu (L) 63 14.2% Lys (K) 27 6.1% Met (M) 7 1.6% Phe (F) 21 4.7% Pro (P) 13 2.9% Ser (S) 48 10.8% Thr (T) 28 6.3% Trp (W) 3 0.7% Tyr (Y) 13 2.9% Val (V) 37 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 2289 Hydrogen H 3668 Nitrogen N 600 Oxygen O 665 Sulfur S 21 Formula: C2289H3668N600O665S21 Total number of atoms: 7243 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36745 Abs 0.1% (=1 g/l) 0.722, assuming all pairs of Cys residues form cystines Ext. coefficient 35870 Abs 0.1% (=1 g/l) 0.705, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 46.46 This classifies the protein as unstable. Aliphatic index: 110.29 Grand average of hydropathicity (GRAVY): 0.063