ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVKVAILGAS GGVGQPLSLL LKLSPYVSEL ALYDIRAAEG IGKDLSHINT NSSCVGYDKD 

        70         80         90        100        110        120 
SIENTLSNAQ VVLIPAGVPR KPGLTRDDLF KMNAGIVKSL VTAVGKFAPN ARILVISNPV 

       130        140        150        160        170        180 
NSLVPIAVET LKKMGKFKPG NVMGVTNLDL VRAETFLVDY LMLKNPKIGQ EQDKTTMHRK 

       190        200        210        220        230        240 
VTVIGGHSGE TIIPIITDKS LVFQLDKQYE HFIHRVQFGG DEIVKAKQGA GSATLSMAFA 

       250        260        270        280        290        300 
GAKFAEEVLR SFHNEKPETE SLSAFVYLPG LKNGKKAQQL VGDNSIEYFS LPIVLRNGSV 

       310        320        330        340 
VSIDTSVLEK LSPREEQLVN TAVKELRKNI EKGKSFILDS SKL 

References and documentation are available.

Number of amino acids: 343

Molecular weight: 37186.16

Theoretical pI: 9.22

Amino acid composition: 
Ala (A)  23	  6.7%
Arg (R)  11	  3.2%
Asn (N)  17	  5.0%
Asp (D)  15	  4.4%
Cys (C)   1	  0.3%
Gln (Q)  11	  3.2%
Glu (E)  20	  5.8%
Gly (G)  28	  8.2%
His (H)   6	  1.7%
Ile (I)  23	  6.7%
Leu (L)  38	 11.1%
Lys (K)  31	  9.0%
Met (M)   7	  2.0%
Phe (F)  13	  3.8%
Pro (P)  15	  4.4%
Ser (S)  28	  8.2%
Thr (T)  16	  4.7%
Trp (W)   0	  0.0%
Tyr (Y)   7	  2.0%
Val (V)  33	  9.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 35
Total number of positively charged residues (Arg + Lys): 42

Atomic composition:

Carbon      C	      1668
Hydrogen    H	      2725
Nitrogen    N	       447
Oxygen      O	       493
Sulfur      S	         8

Formula: C1668H2725N447O493S8
Total number of atoms: 5341

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.280, assuming all pairs of Cys residues form cystines


Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.280, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 31.04
This classifies the protein as stable.



Aliphatic index: 103.97

Grand average of hydropathicity (GRAVY): -0.023