ProtParam
User-provided sequence:
10 20 30 40 50 60
MVKVWNIVLR LVVLLFLAGN TLLLILMIIS GATDHYPVNR FYWVQGNTTG IPNAGDETRW
70 80 90 100 110 120
TFWGACLQDK DGSDTCTSNL APAYPISPVD NFNTHINVPH QFISKRDAFY YLTRFSFCFF
130 140 150 160 170 180
WIALAFVGVS FILYVLTWCS KMLSEMVLIL MSFGFVFNTA AVVLQTAASA MAKNAFHDDH
190 200 210 220 230 240
RSAQLGASMM GMAWASVFLC IVEFILLVFW SVRARLASTY SIDNSRYRTS SRWNPFHREK
250 260 270 280 290 300
EQATDPILTA TGPEDMQQSA SIVGPSSNAN PVTATAATEN QPKGINFFTI RKSHERPDDV
SV
References and
documentation are available.
Number of amino acids: 302
Molecular weight: 33829.87
Theoretical pI: 7.04
Total number of negatively charged residues (Asp + Glu): 22
Total number of positively charged residues (Arg + Lys): 22
Atomic composition:
Carbon C 1541
Hydrogen H 2341
Nitrogen N 401
Oxygen O 429
Sulfur S 15
Formula: C
1541H
2341N
401O
429S
15
Total number of atoms: 4727
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 61670
Abs 0.1% (=1 g/l) 1.823, assuming all pairs of Cys residues form cystines
Ext. coefficient 61420
Abs 0.1% (=1 g/l) 1.816, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 41.10
This classifies the protein as unstable.
Aliphatic index: 88.18
Grand average of hydropathicity (GRAVY): 0.187