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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVLKSTSAND VSVYQVSGTN VSRSLPDWIA KKRKRQLKND LEYQNRVELI QDFEFSEASN

70 80 90 100 110 120
KIKVSRDGQY CMATGTYKPQ IHVYDFANLS LKFDRHTDAE NVDFTILSDD WTKSVHLQND

130 140 150 160 170 180
RSIQFQNKGG LHYTTRIPKF GRSLVYNKVN CDLYVGASGN ELYRLNLEKG RFLNPFKLDT

190 200 210 220 230 240
EGVNHVSINE VNGLLAAGTE TNVVEFWDPR SRSRVSKLYL ENNIDNRPFQ VTTTSFRNDG

250 260 270 280 290 300
LTFACGTSNG YSYIYDLRTS EPSIIKDQGY GFDIKKIIWL DNVGTENKIV TCDKRIAKIW

310 320 330 340 350 360
DRLDGKAYAS MEPSVDINDI EHVPGTGMFF TANESIPMHT YYIPSLGPSP RWCSFLDSIT

370 380 390 400 410 420
EELEEKPSDT VYSNYRFITR DDVKKLNLTH LVGSRVLRAY MHGFFINTEL YDKVSLIANP

430 440 450 460 470 480
DAYKDERERE IRRRIEKERE SRIRSSGAVQ KPKIKVNKTL VDKLSQKRGD KVAGKVLTDD

490 500 510 520 530 540
RFKEMFEDEE FQVDEDDYDF KQLNPVKSIK ETEEGAAKRI RALTAAEESD EERIAMKDGR

550 560 570 580 590 600
GHYDYEDEES DEEESDDETN QKSNKEELSE KDLRKMEKQK ALIERRKKEK EQSERFMNEM

610 620 630 640 650 660
KAGTSTSTQR DESAHVTFGE QVGELLEVEN GKKSNESILR RNQRGEAELT FIPQRKSKKD

670 680 690 700
GNYKSRRHDN SSDEEGIEEN GNKKDNGRSK PRFENRRRAS KNAFRGM


References and documentation are available.

Number of amino acids: 707 Molecular weight: 81748.05 Theoretical pI: 6.20
Amino acid composition: 
Ala (A) 31 4.4% Arg (R) 55 7.8% Asn (N) 46 6.5% Asp (D) 55 7.8% Cys (C) 5 0.7% Gln (Q) 22 3.1% Glu (E) 69 9.8% Gly (G) 40 5.7% His (H) 12 1.7% Ile (I) 37 5.2% Leu (L) 46 6.5% Lys (K) 63 8.9% Met (M) 12 1.7% Phe (F) 29 4.1% Pro (P) 19 2.7% Ser (S) 57 8.1% Thr (T) 38 5.4% Trp (W) 6 0.8% Tyr (Y) 26 3.7% Val (V) 39 5.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 124 Total number of positively charged residues (Arg + Lys): 118 Atomic composition: Carbon C 3559 Hydrogen H 5623 Nitrogen N 1033 Oxygen O 1145 Sulfur S 17 Formula: C3559H5623N1033O1145S17 Total number of atoms: 11377 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 71990 Abs 0.1% (=1 g/l) 0.881, assuming all pairs of Cys residues form cystines Ext. coefficient 71740 Abs 0.1% (=1 g/l) 0.878, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.40 This classifies the protein as unstable. Aliphatic index: 66.17 Grand average of hydropathicity (GRAVY): -0.967