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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVLQKLPLIG LLLLLTIVAS PANADGPVCP PSNKLSRASF PEGFLFGTAT AAYQVEGAIN

70 80 90 100 110 120
ETCRGPALWD IYCRRYPERC NNDNGDVAVD FFHRYKEDIQ LMKNLNTDAF RMSIAWPRIF

130 140 150 160 170 180
PHGRKEKGVS QAGVQFYHDL IDELIKNGIT PFVTVFHWDT PQDLEDEYGG FLSERIVKDF

190 200 210 220 230 240
REYADFVFQE YGGKVKHWIT FNEPWVFSHA GYDVGKKAPG RCSSYVNAKC QDGRSGYEAY

250 260 270 280 290 300
LVTHNLLISH AEAVEAYRKC EKCKGGKIGI AHSPAWFEAH DLADSQDGAS IDRALDFILG

310 320 330 340 350 360
WHLDTTTFGD YPQIMKDIVG HRLPKFTTEQ KAKLKASTDF VGLNYYTSVF SNHLEKPDPS

370 380 390 400 410 420
KPRWMQDSLI TWESKNAQNY AIGSKPLTAA LNVYSRGFRS LLKYIKDKYA NPEIMIMENG

430 440 450 460 470 480
YGEELGASDS VAVGTADHNR KYYLQRHLLS MQEAVCIDKV NVTGYFVWSL LDNFEWQDGY

490 500 510 520
KNRFGLYYVD FKNNLTRYEK ESGKYYKDFL SQGVRPSALK KDEL


References and documentation are available.

Number of amino acids: 524 Molecular weight: 59720.57 Theoretical pI: 6.45
Amino acid composition: 
Ala (A) 39 7.4% Arg (R) 24 4.6% Asn (N) 25 4.8% Asp (D) 36 6.9% Cys (C) 9 1.7% Gln (Q) 17 3.2% Glu (E) 30 5.7% Gly (G) 39 7.4% His (H) 15 2.9% Ile (I) 25 4.8% Leu (L) 44 8.4% Lys (K) 38 7.3% Met (M) 8 1.5% Phe (F) 28 5.3% Pro (P) 23 4.4% Ser (S) 31 5.9% Thr (T) 22 4.2% Trp (W) 11 2.1% Tyr (Y) 30 5.7% Val (V) 30 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 66 Total number of positively charged residues (Arg + Lys): 62 Atomic composition: Carbon C 2706 Hydrogen H 4087 Nitrogen N 717 Oxygen O 782 Sulfur S 17 Formula: C2706H4087N717O782S17 Total number of atoms: 8309 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 105700 Abs 0.1% (=1 g/l) 1.770, assuming all pairs of Cys residues form cystines Ext. coefficient 105200 Abs 0.1% (=1 g/l) 1.762, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 27.14 This classifies the protein as stable. Aliphatic index: 75.40 Grand average of hydropathicity (GRAVY): -0.442