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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVLRIRRIKK LAPLIFTSLL SLIVLFRVYR QYPFSDHFET RREDDRSGNV HCFSRLRQIE

70 80 90 100 110 120
EYEKPELTSK FYEPNRWKSF ISYVTRSRKD VKTVSRSLSN LDLYQKCSKE IRADQDISLL

130 140 150 160 170 180
HSIETKLFPY INFTALNSEQ SHNFWPVHTR FDGTKYRGQV LQFSSENNSF IGTSPIEFKA

190 200 210 220 230 240
SEPFWENWLN SALQRNSKGV VMSVSEYLVA DTIRLIRVLR LLNNSLPIEI VHKSDLHESS

250 260 270 280 290 300
QQLLIAAARE SGSLNYPPQE LWFLDVKDML NDEYLARFKR FSNKWLAITF CSFQIPIFLD

310 320 330 340 350 360
SDTVPFVPLD TLYEIDGFKR TGTLFFKDRS FPTSKLSPLQ VKVLKQIINN SLDVSSDSEQ

370 380 390 400 410 420
GFEILKHNLN DEMAIDAIEA LIFKKQKHYM DSGLVIFDKQ KHFFCLPIAI MLQFSPIQEF

430 440 450 460 470 480
FHGDKEWFWL SLFISKKEFT FYPIEASNVG RLEKPETLES STICSTQLSH TDVYGNLLWL

490 500 510 520 530 540
NGGLSVCKKN CWNYDFTKRK EIAAKYKSVD ELRNYYQSPV KLEAVIIPDV SKSPWSQQSE

550 560 570 580
CVMYSYCTHY RKGQYGKLIE FTDSQKKYYE KVVELWNKVV


References and documentation are available.

Number of amino acids: 580 Molecular weight: 68082.01 Theoretical pI: 8.67
Amino acid composition: 
Ala (A) 19 3.3% Arg (R) 30 5.2% Asn (N) 27 4.7% Asp (D) 30 5.2% Cys (C) 9 1.6% Gln (Q) 25 4.3% Glu (E) 39 6.7% Gly (G) 17 2.9% His (H) 13 2.2% Ile (I) 38 6.6% Leu (L) 61 10.5% Lys (K) 46 7.9% Met (M) 7 1.2% Phe (F) 40 6.9% Pro (P) 23 4.0% Ser (S) 60 10.3% Thr (T) 25 4.3% Trp (W) 12 2.1% Tyr (Y) 25 4.3% Val (V) 34 5.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 69 Total number of positively charged residues (Arg + Lys): 76 Atomic composition: Carbon C 3111 Hydrogen H 4780 Nitrogen N 806 Oxygen O 881 Sulfur S 16 Formula: C3111H4780N806O881S16 Total number of atoms: 9594 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 103750 Abs 0.1% (=1 g/l) 1.524, assuming all pairs of Cys residues form cystines Ext. coefficient 103250 Abs 0.1% (=1 g/l) 1.517, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 54.84 This classifies the protein as unstable. Aliphatic index: 86.84 Grand average of hydropathicity (GRAVY): -0.352