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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVLRNLTISY EIIKSLKHAK EHSLGIQIRW ISSLKVVWKK DTRLDEAIEQ DKRYKLCARV

70 80 90 100 110 120
VKEVLNEPGQ VIPLRYLEKR RERLRLTFKA KSFVEMNPSL FEIYYDRIKP KSDPVQFLRP

130 140 150 160 170 180
TPRLRAFLDE EQRIYSENEP LLVSKLCQLL MMAKDKVISA DKLVHVKRDF GFPNDFLMKL

190 200 210 220 230 240
VQKYPNYFRL TGLPEEGKSF LELVSWNPDF AKSKIELRAE DETLKTGVRI RPNYNVKLPS

250 260 270 280 290 300
GFFLRKEMRE WTRDWLEQDY ISPYEDVSHL DQASKEMEKR TVGVVHELLS LSLLKRVPVP

310 320 330 340 350 360
TLGKFCDEFR FSNAFSSVFT RHSGIFYLSL KGGIKTAVLR EAYKDDELVD RDPLLAIKDK

370 380 390 400
FLRLLEEGWQ ERKDRLKLQR EQVQKDREMM LAAKSNEPIE RLCD


References and documentation are available.

Number of amino acids: 404 Molecular weight: 47810.61 Theoretical pI: 9.32
Amino acid composition: 
Ala (A) 16 4.0% Arg (R) 35 8.7% Asn (N) 11 2.7% Asp (D) 25 6.2% Cys (C) 4 1.0% Gln (Q) 13 3.2% Glu (E) 37 9.2% Gly (G) 13 3.2% His (H) 6 1.5% Ile (I) 19 4.7% Leu (L) 53 13.1% Lys (K) 40 9.9% Met (M) 9 2.2% Phe (F) 20 5.0% Pro (P) 19 4.7% Ser (S) 26 6.4% Thr (T) 12 3.0% Trp (W) 6 1.5% Tyr (Y) 13 3.2% Val (V) 27 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 62 Total number of positively charged residues (Arg + Lys): 75 Atomic composition: Carbon C 2162 Hydrogen H 3457 Nitrogen N 591 Oxygen O 604 Sulfur S 13 Formula: C2162H3457N591O604S13 Total number of atoms: 6827 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 52620 Abs 0.1% (=1 g/l) 1.101, assuming all pairs of Cys residues form cystines Ext. coefficient 52370 Abs 0.1% (=1 g/l) 1.095, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.97 This classifies the protein as stable. Aliphatic index: 92.85 Grand average of hydropathicity (GRAVY): -0.516