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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVLSVKQTLS PKIGLFRRNP SSSLGRSPVS LSFPSTELPK RTVLAVSKPL HLSSSLRAKS

70 80 90 100 110 120
PVVRCEAYEA DRSEPHPIGD DAAAAETKSE AAKKLKIGIY FATWWALNVV FNIYNKKVLN

130 140 150 160 170 180
AYPYPWLTST LSLAAGSLMM LISWAVGIVE TPKTDFDFWK TLFPVAVAHT IGHVAATVSM

190 200 210 220 230 240
SKVAVSFTHI IKSGEPAFSV LVSRFILGET FPTSVYLSLI PIIGGCALSA LTELNFNMIG

250 260 270 280 290 300
FMGAMISNLA FVFRNIFSKK GMKGKSVSGM NYYACLSMLS LLILTPFAIA VEGPQMWVDG

310 320 330 340 350 360
WQTALATVGP QFVWWVVAQS VFYHLYNQVS YMSLDQISPL TFSVGNTMKR ISVIVSSIII

370 380
FRTPVQPVNA LGAAIAILGT FLYSQAKL


References and documentation are available.

Number of amino acids: 388 Molecular weight: 42328.77 Theoretical pI: 9.67
Amino acid composition: 
Ala (A) 37 9.5% Arg (R) 11 2.8% Asn (N) 13 3.4% Asp (D) 7 1.8% Cys (C) 3 0.8% Gln (Q) 9 2.3% Glu (E) 11 2.8% Gly (G) 22 5.7% His (H) 6 1.5% Ile (I) 27 7.0% Leu (L) 40 10.3% Lys (K) 21 5.4% Met (M) 13 3.4% Phe (F) 22 5.7% Pro (P) 22 5.7% Ser (S) 44 11.3% Thr (T) 23 5.9% Trp (W) 9 2.3% Tyr (Y) 12 3.1% Val (V) 36 9.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 18 Total number of positively charged residues (Arg + Lys): 32 Atomic composition: Carbon C 1958 Hydrogen H 3065 Nitrogen N 485 Oxygen O 526 Sulfur S 16 Formula: C1958H3065N485O526S16 Total number of atoms: 6050 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 67505 Abs 0.1% (=1 g/l) 1.595, assuming all pairs of Cys residues form cystines Ext. coefficient 67380 Abs 0.1% (=1 g/l) 1.592, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.05 This classifies the protein as unstable. Aliphatic index: 103.79 Grand average of hydropathicity (GRAVY): 0.452