ProtParam
User-provided sequence:
10 20 30 40 50 60
MVLSVKQTLS PKIGLFRRNP SSSLGRSPVS LSFPSTELPK RTVLAVSKPL HLSSSLRAKS
70 80 90 100 110 120
PVVRCEAYEA DRSEPHPIGD DAAAAETKSE AAKKLKIGIY FATWWALNVV FNIYNKKVLN
130 140 150 160 170 180
AYPYPWLTST LSLAAGSLMM LISWAVGIVE TPKTDFDFWK TLFPVAVAHT IGHVAATVSM
190 200 210 220 230 240
SKVAVSFTHI IKSGEPAFSV LVSRFILGET FPTSVYLSLI PIIGGCALSA LTELNFNMIG
250 260 270 280 290 300
FMGAMISNLA FVFRNIFSKK GMKGKSVSGM NYYACLSMLS LLILTPFAIA VEGPQMWVDG
310 320 330 340 350 360
WQTALATVGP QFVWWVVAQS VFYHLYNQVS YMSLDQISPL TFSVGNTMKR ISVIVSSIII
370 380
FRTPVQPVNA LGAAIAILGT FLYSQAKL
References and
documentation are available.
Number of amino acids: 388
Molecular weight: 42328.77
Theoretical pI: 9.67
Total number of negatively charged residues (Asp + Glu): 18
Total number of positively charged residues (Arg + Lys): 32
Atomic composition:
Carbon C 1958
Hydrogen H 3065
Nitrogen N 485
Oxygen O 526
Sulfur S 16
Formula: C
1958H
3065N
485O
526S
16
Total number of atoms: 6050
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 67505
Abs 0.1% (=1 g/l) 1.595, assuming all pairs of Cys residues form cystines
Ext. coefficient 67380
Abs 0.1% (=1 g/l) 1.592, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 42.05
This classifies the protein as unstable.
Aliphatic index: 103.79
Grand average of hydropathicity (GRAVY): 0.452