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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVLVQDLLHP TAASEARKHK LKTLVQGPRS YFLDVKCPGC LNITTVFSHA QTAVTCESCS

70 80
TILCTPTGGK AKLSEGTSFR RK


References and documentation are available.

Number of amino acids: 82 Molecular weight: 8879.37 Theoretical pI: 9.36
Amino acid composition: 
Ala (A) 6 7.3% Arg (R) 4 4.9% Asn (N) 1 1.2% Asp (D) 2 2.4% Cys (C) 5 6.1% Gln (Q) 3 3.7% Glu (E) 3 3.7% Gly (G) 5 6.1% His (H) 3 3.7% Ile (I) 2 2.4% Leu (L) 9 11.0% Lys (K) 7 8.5% Met (M) 1 1.2% Phe (F) 3 3.7% Pro (P) 4 4.9% Ser (S) 7 8.5% Thr (T) 10 12.2% Trp (W) 0 0.0% Tyr (Y) 1 1.2% Val (V) 6 7.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 5 Total number of positively charged residues (Arg + Lys): 11 Atomic composition: Carbon C 387 Hydrogen H 639 Nitrogen N 111 Oxygen O 115 Sulfur S 6 Formula: C387H639N111O115S6 Total number of atoms: 1258 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 1740 Abs 0.1% (=1 g/l) 0.196, assuming all pairs of Cys residues form cystines Ext. coefficient 1490 Abs 0.1% (=1 g/l) 0.168, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.50 This classifies the protein as unstable. Aliphatic index: 80.85 Grand average of hydropathicity (GRAVY): -0.082