ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVMADTIATG DKTSQFDGKH MQDLERIYST RDTLDDNFFG ERGQKDANGD YYDELNNEET 

        70         80         90        100        110        120 
NYSGSSYYGH SDDSEVVGLI KNDTVSQLPP LDSFIFPDSR ALFLLDLGNY ADLTYEEIIV 

       130        140        150        160        170        180 
HGFEIYIVEQ WVACRNLSTL ITSYTGNSQD TISGVRVVLP KDTSMWPGRF RLYFEELMEF 

       190        200        210        220        230        240 
ARPKFTPKGT LFITNLSGVS FGLNLLHVEC GDLRTIWKDF EVNFDLKNLH CGGRSANLLC 

       250        260        270        280        290        300 
PPTMASLDKF SQLFKIPTNG FIAQYPQMIQ QQQPRLPEEE YKTVGNSKCR NTDSKSPVVE 

       310        320        330        340        350        360 
MVTLIQISLS YFNLLSKNYQ TDGLLCEDTK RAIDEWWETY GKLYLGTEKP RNECTLGPTT 

       370        380        390        400        410        420 
VAGLISLILC CYFKLMIENC ISSKDPFDEA GFFQGIYNFQ KKHGLNKRKS RVYLDPRTLE 

       430        440        450        460        470        480 
KLFEVTAKVS SKDIFKLKKM VTSTVQDIIG KGNPINLSHK ILTTDLDTLI HNIHGGSVGL 

       490        500        510        520        530        540 
LWKGKGHPRK CCTDISNEEF LKFNYQRGDP DGQIREREML LEKFRLERIA YAQKHASKKV 

       550        560        570        580        590        600 
SSSSLDTSED IGRTNAMPSS ATVSSMFPNY DNTKYAYNFG INKLYQGEYY RRNSFPYCKD 

       610        620        630        640        650        660 
RTHDNIYEDL SELKEKSSRL YRCNSSSAVQ NIVEKWDLPF DPSVVRIARD LLRMKYDIQA 

       670        680        690        700        710        720 
QQHIQEMDEH YMGKLNKEGT VGQYSKFNER YKRLQELYKK YSDGAKVFEG RFEDIDNKQQ 

       730        740        750        760        770        780 
LLLHEMQELN SLSSRLKYDM RILEVRVRDI ESSVAQFDSK LIGLKSSLQG QGKTGICSAI 

       790        800        810        820        830        840 
DPKSDKDEYD RCVNDLMTTN NPTYEALCLK MLSRRYFKDL KNDTVGWFRW LFGNNSLHNN 

       850 
ASEDDRGIRV 

References and documentation are available.

Number of amino acids: 850

Molecular weight: 97827.68

Theoretical pI: 6.22

Amino acid composition: 
Ala (A)  28	  3.3%
Arg (R)  46	  5.4%
Asn (N)  49	  5.8%
Asp (D)  63	  7.4%
Cys (C)  17	  2.0%
Gln (Q)  35	  4.1%
Glu (E)  54	  6.4%
Gly (G)  53	  6.2%
His (H)  16	  1.9%
Ile (I)  47	  5.5%
Leu (L)  85	 10.0%
Lys (K)  64	  7.5%
Met (M)  20	  2.4%
Phe (F)  40	  4.7%
Pro (P)  28	  3.3%
Ser (S)  69	  8.1%
Thr (T)  48	  5.6%
Trp (W)   9	  1.1%
Tyr (Y)  41	  4.8%
Val (V)  38	  4.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 117
Total number of positively charged residues (Arg + Lys): 110

Atomic composition:

Carbon      C	      4339
Hydrogen    H	      6755
Nitrogen    N	      1177
Oxygen      O	      1327
Sulfur      S	        37

Formula: C4339H6755N1177O1327S37
Total number of atoms: 13635

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   111590
Abs 0.1% (=1 g/l)   1.141, assuming all pairs of Cys residues form cystines


Ext. coefficient   110590
Abs 0.1% (=1 g/l)   1.130, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.37
This classifies the protein as stable.



Aliphatic index: 76.82

Grand average of hydropathicity (GRAVY): -0.577