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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVMEERSCHT ANRVGDVQMG NGHKRGRSED SSSNNVSIGV ETDKQDMLSN KAQKKWVFGK

70 80 90 100 110 120
CVNLSAVDAP CFKEMMTVDG GQMGLESSDC HDLNGWRLQD ALEEVQDRVE KIKESWAITG

130 140 150 160 170 180
CSILLDAWVD QKGRDLVTFV ADCPAGLVYL ISFDVSDFKD DVTALLSLVN GLVEEVGVRN

190 200 210 220 230 240
VTQIIACSTS GWVGELGELF AGHDREVFWS VSVSHCFELM LVKISKIRSF GDIFDKVNNI

250 260 270 280 290 300
WLFINNNPSV LNIFRDQCHG IDITVSSSEF EFVTPYLILE SIFKAKKNLT AMFASSNWNN

310 320 330 340 350 360
EQCIAISNLV SDSSFWETVE SVLKCTSPLI HGLLLFSTAN NQHLGYVYDT MDSIKESIAR

370 380 390 400 410 420
EFNHKPQFYK PLWDVIDDVW NKHLHNPLHA AGYFLNPTAF YSTNFHLDIE VVTGLISSLI

430 440 450 460 470 480
HMVEDCHVQF KISTQIDMYR LGKDCFNEAS QADQITGISP AEWWAHKASQ YPELQSLAIK

490 500 510 520 530 540
ILSQTCEGAS KYKLKRSLAE KLLLSEGMSN RERQHLDELV FVQYNLHLQS YKAKLSEEID


VYKD


References and documentation are available.

Number of amino acids: 544 Molecular weight: 61455.71 Theoretical pI: 5.17
Amino acid composition: 
Ala (A) 30 5.5% Arg (R) 16 2.9% Asn (N) 30 5.5% Asp (D) 37 6.8% Cys (C) 14 2.6% Gln (Q) 22 4.0% Glu (E) 36 6.6% Gly (G) 29 5.3% His (H) 18 3.3% Ile (I) 33 6.1% Leu (L) 52 9.6% Lys (K) 33 6.1% Met (M) 13 2.4% Phe (F) 26 4.8% Pro (P) 11 2.0% Ser (S) 53 9.7% Thr (T) 21 3.9% Trp (W) 13 2.4% Tyr (Y) 13 2.4% Val (V) 44 8.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 73 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 2737 Hydrogen H 4234 Nitrogen N 726 Oxygen O 830 Sulfur S 27 Formula: C2737H4234N726O830S27 Total number of atoms: 8554 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 91745 Abs 0.1% (=1 g/l) 1.493, assuming all pairs of Cys residues form cystines Ext. coefficient 90870 Abs 0.1% (=1 g/l) 1.479, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.07 This classifies the protein as stable. Aliphatic index: 89.91 Grand average of hydropathicity (GRAVY): -0.172