ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVMQTEARVG VSSGHGVASS SHRLTQDQRS HIESASQLLA GGLAGAFSKT CTAPLSRLTI 

        70         80         90        100        110        120 
LFQVQGMHTN AAALRKPSIL HEASRILNEE GLKAFWKGNL VTIAHRLPYS SVNFYAYEHY 

       130        140        150        160        170        180 
KKFMYMVTGM ENHKEGISSN LFVHFVAGGL AGITAASATY PLDLVRTRLA AQTKVIYYSG 

       190        200        210        220        230        240 
IWHTLRSITT DEGILGLYKG LGTTLVGVGP SIAISFSVYE SLRSYWRSTR PHDSPIMVSL 

       250        260        270        280        290        300 
ACGSLSGIAS STATFPLDLV RRRKQLEGIG GRAVVYKTGL LGTLKRIVQT EGARGLYRGI 

       310        320        330 
LPEYYKVVPG VGICFMTYET LKLYFKDLSS NL 

References and documentation are available.

Number of amino acids: 332

Molecular weight: 36237.86

Theoretical pI: 9.74

Amino acid composition: 
Ala (A)  27	  8.1%
Arg (R)  20	  6.0%
Asn (N)   7	  2.1%
Asp (D)   6	  1.8%
Cys (C)   3	  0.9%
Gln (Q)   9	  2.7%
Glu (E)  14	  4.2%
Gly (G)  33	  9.9%
His (H)  11	  3.3%
Ile (I)  19	  5.7%
Leu (L)  38	 11.4%
Lys (K)  15	  4.5%
Met (M)   8	  2.4%
Phe (F)  11	  3.3%
Pro (P)  10	  3.0%
Ser (S)  33	  9.9%
Thr (T)  25	  7.5%
Trp (W)   3	  0.9%
Tyr (Y)  17	  5.1%
Val (V)  23	  6.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	      1630
Hydrogen    H	      2588
Nitrogen    N	       448
Oxygen      O	       464
Sulfur      S	        11

Formula: C1630H2588N448O464S11
Total number of atoms: 5141

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    41955
Abs 0.1% (=1 g/l)   1.158, assuming all pairs of Cys residues form cystines


Ext. coefficient    41830
Abs 0.1% (=1 g/l)   1.154, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.51
This classifies the protein as unstable.



Aliphatic index: 95.18

Grand average of hydropathicity (GRAVY): 0.063