ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVNLGNAVRS LLMHLIGLLV WQFDISISPV AAIVTDTFNS SDGGRLFQFP DGVQNWPALS 

        70         80         90        100        110        120 
IVVIIIMTIG GNILVIMAVS MEKKLHNATN YFLMSLAIAD MLVGLLVMPL SLLAILYDYV 

       130        140        150        160        170        180 
WPLPRYLCPV WISLDVLFST ASIMHLCAIS LDRYVAIRNP IEHSRFNSRT KAIMKIAIVW 

       190        200        210        220        230        240 
AISIGVSVPI PVIGLRDESK VFVNNTTCVL NDPNFVLIGS FVAFFIPLTI MVITYFLTIY 

       250        260        270        280        290        300 
VLRRQTLMLL RGHTEEELAN MSLNFLNCCC KKNGGEEENA PNPNPDQKPR RKKKEKRPRG 

       310        320        330        340        350        360 
TMQAINNEKK ASKVLGIVFF VFLIMWCPFF ITNILSVLCG KACNQKLMEK LLNVFVWIGY 

       370        380        390        400        410        420 
VCSGINPLVY TLFNKIYRRA FSKYLRCDYK PDKKPPVRQI PRVAATALSG RELNVNIYRH 

       430        440        450        460 
TNERVARKAN DPEPGIEMQV ENLELPVNPS NVVSERISSV 

References and documentation are available.

Number of amino acids: 460

Molecular weight: 51916.52

Theoretical pI: 9.38

Amino acid composition: 
Ala (A)  27	  5.9%
Arg (R)  25	  5.4%
Asn (N)  34	  7.4%
Asp (D)  14	  3.0%
Cys (C)  11	  2.4%
Gln (Q)   9	  2.0%
Glu (E)  19	  4.1%
Gly (G)  21	  4.6%
His (H)   6	  1.3%
Ile (I)  42	  9.1%
Leu (L)  51	 11.1%
Lys (K)  24	  5.2%
Met (M)  17	  3.7%
Phe (F)  22	  4.8%
Pro (P)  27	  5.9%
Ser (S)  29	  6.3%
Thr (T)  18	  3.9%
Trp (W)   7	  1.5%
Tyr (Y)  13	  2.8%
Val (V)  44	  9.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 33
Total number of positively charged residues (Arg + Lys): 49

Atomic composition:

Carbon      C	      2367
Hydrogen    H	      3781
Nitrogen    N	       621
Oxygen      O	       630
Sulfur      S	        28

Formula: C2367H3781N621O630S28
Total number of atoms: 7427

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    58495
Abs 0.1% (=1 g/l)   1.127, assuming all pairs of Cys residues form cystines


Ext. coefficient    57870
Abs 0.1% (=1 g/l)   1.115, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.85
This classifies the protein as stable.



Aliphatic index: 112.46

Grand average of hydropathicity (GRAVY): 0.295