ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVNVGPSHAA VAVDASEARK RNISEEVFEL RDKKDSTVVI EGEAPVRTFT SSSSNHERED 

        70         80         90        100        110        120 
TYVSKRQVMR DIFAKYLKFI GPGLMVSVAY IDPGNYSTAV DAGASNQFSL LCIILLSNFI 

       130        140        150        160        170        180 
AIFLQCLCIK LGSVTGLDLS RACREYLPRW LNWTLYFFAE CAVIATDIAE VIGTAIALNI 

       190        200        210        220        230        240 
LIKVPLPAGV AITVVDVFLI MFTYKPGASS IRFIRIFECF VAVLVVGVCI CFAIELAYIP 

       250        260        270        280        290        300 
KSTSVKQVFR GFVPSAQMFD HNGIYTAISI LGATVMPHSL FLGSALVQPR LLDYDVKHGN 

       310        320        330        340        350        360 
YTVSEEQDKV KKSKSTEEIM EEKYFNYRPT NAAIKYCMKY SMVELSITLF TLALFVNCAI 

       370        380        390        400        410        420 
LVVAGSTLYN SPEADGADLF TIHELLSRNL APAAGTIFML ALLLSGQSAG VVCTMSGQIV 

       430        440        450        460        470        480 
SEGHINWKLQ PWQRRLATRC ISIIPCLVIS ICIGREALSK ALNASQVVLS IVLPFLVAPL 

       490        500        510        520        530        540 
IFFTCKKSIM KTEITVDHTE EDSHNHQNNN DRSAGSVIEQ DGSSGMEIEN GKDVKIVYMA 

       550        560        570 
NNWIITVIAI IVWLFLSLLN VYAIVQLGMS HGDIS 

References and documentation are available.

Number of amino acids: 575

Molecular weight: 63263.78

Theoretical pI: 6.16

Amino acid composition: 
Ala (A)  50	  8.7%
Arg (R)  21	  3.7%
Asn (N)  25	  4.3%
Asp (D)  22	  3.8%
Cys (C)  15	  2.6%
Gln (Q)  15	  2.6%
Glu (E)  30	  5.2%
Gly (G)  31	  5.4%
His (H)  11	  1.9%
Ile (I)  55	  9.6%
Leu (L)  55	  9.6%
Lys (K)  26	  4.5%
Met (M)  15	  2.6%
Phe (F)  28	  4.9%
Pro (P)  19	  3.3%
Ser (S)  50	  8.7%
Thr (T)  29	  5.0%
Trp (W)   6	  1.0%
Tyr (Y)  18	  3.1%
Val (V)  54	  9.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 52
Total number of positively charged residues (Arg + Lys): 47

Atomic composition:

Carbon      C	      2864
Hydrogen    H	      4542
Nitrogen    N	       732
Oxygen      O	       817
Sulfur      S	        30

Formula: C2864H4542N732O817S30
Total number of atoms: 8985

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    60695
Abs 0.1% (=1 g/l)   0.959, assuming all pairs of Cys residues form cystines


Ext. coefficient    59820
Abs 0.1% (=1 g/l)   0.946, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.89
This classifies the protein as unstable.



Aliphatic index: 110.54

Grand average of hydropathicity (GRAVY): 0.405