ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVQSAVLGFP RIGPNRELKK ATEGYWNGKI TVDELFKVGK DLRTQNWKLQ KEAGVDIIPS 

        70         80         90        100        110        120 
NDFSFYDQVL DLSLLFNVIP DRYTKYDLSP IDTLFAMGRG LQRKATETEK AVDVTALEMV 

       130        140        150        160        170        180 
KWFDSNYHYV RPTFSKTTQF KLNGQKPVDE FLEAKELGIH TRPVLLGPVS YLFLGKADKD 

       190        200        210        220        230        240 
SLDLEPLSLL EQLLPLYTEI LSKLASAGAT EVQIDEPVLV LDLPANAQAA IKKAYTYFGE 

       250        260        270        280        290        300 
QSNLPKITLA TYFGTVVPNL DAIKGLPVAA LHVDFVRAPE QFDEVVAAIG NKQTLSVGIV 

       310        320        330        340        350        360 
DGRNIWKNDF KKSSAIVNKA IEKLGADRVV VATSSSLLHT PVDLNNETKL DAEIKGFFSF 

       370        380        390        400        410        420 
ATQKLDEVVV ITKNVSGQDV AAALEANAKS VESRGKSKFI HDAAVKARVA SIDEKMSTRA 

       430        440        450        460        470        480 
APFEQRLPEQ QKVFNLPLFP TTTIGSFPQT KDIRINRNKF NKGTISAEEY EKFINSEIEK 

       490        500        510        520        530        540 
VIRFQEEIGL DVLVHGEPER NDMVQYFGEQ INGYAFTVNG WVQSYGSRYV RPPIIVGDLS 

       550        560        570        580        590        600 
RPKAMSVKES VYAQSITSKP VKGMLTGPIT CLRWSFPRDD VDQKTQAMQL ALALRDEVND 

       610        620        630        640        650        660 
LEAAGIKVIQ VDEPALREGL PLREGTERSA YYTWAAEAFR VATSGVANKT QIHSHFCYSD 

       670        680        690        700        710        720 
LDPNHIKALD ADVVSIEFSK KDDANYIAEF KNYPNHIGLG LFDIHSPRIP SKDEFIAKIS 

       730        740        750        760 
TILKSYPAEK FWVNPDCGLK TRGWEETRLS LTHMVEAAKY FREQYKN 

References and documentation are available.

Number of amino acids: 767

Molecular weight: 85859.95

Theoretical pI: 6.07

Amino acid composition: 
Ala (A)  65	  8.5%
Arg (R)  33	  4.3%
Asn (N)  34	  4.4%
Asp (D)  48	  6.3%
Cys (C)   3	  0.4%
Gln (Q)  30	  3.9%
Glu (E)  53	  6.9%
Gly (G)  42	  5.5%
His (H)  12	  1.6%
Ile (I)  46	  6.0%
Leu (L)  69	  9.0%
Lys (K)  61	  8.0%
Met (M)   9	  1.2%
Phe (F)  38	  5.0%
Pro (P)  38	  5.0%
Ser (S)  48	  6.3%
Thr (T)  43	  5.6%
Trp (W)   9	  1.2%
Tyr (Y)  25	  3.3%
Val (V)  61	  8.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 101
Total number of positively charged residues (Arg + Lys): 94

Atomic composition:

Carbon      C	      3879
Hydrogen    H	      6094
Nitrogen    N	      1024
Oxygen      O	      1150
Sulfur      S	        12

Formula: C3879H6094N1024O1150S12
Total number of atoms: 12159

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    86875
Abs 0.1% (=1 g/l)   1.012, assuming all pairs of Cys residues form cystines


Ext. coefficient    86750
Abs 0.1% (=1 g/l)   1.010, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.76
This classifies the protein as stable.



Aliphatic index: 90.01

Grand average of hydropathicity (GRAVY): -0.281