ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVRDLVTLPS SLPLITAGFA TDQVHLLIGT GSTDSVSVCK NRIHSILNAG GNPIVVNPSS 

        70         80         90        100        110        120 
PSHTKQLQLE FGKFAKFEIV EREFRLSDLT TLGRVLVCKV VDRVFVDLPI TQSRLCEEIF 

       130        140        150        160        170        180 
WQCQKLRIPI NTFHKPEFST FNMIPTWVDP KGSGLQISVT TNGNGYILAN RIKRDIISHL 

       190        200        210        220        230        240 
PPNISEVVIN MGYLKDRIIN EDHKALLEEK YYQTDMSLPG FGYGLDEDGW ESHKFNKLIR 

       250        260        270        280        290        300 
EFEMTSREQR LKRTRWLSQI MEYYPMNKLS DIKLEDFETS SSPNKKTKQE TVTEGVVPPT 

       310        320        330        340        350        360 
DENIENGTKQ LQLSEVKKEE GPKKLGKISL VGSGPGSVSM LTIGALQEIK SADIILADKL 

       370        380        390        400        410        420 
VPQAILDLIP PKTETFIAKK FPGNAERAQQ ELLAKGLESL DNGLKVVRLK QGDPYIFGRG 

       430        440        450        460        470        480 
GEEFNFFKDH GYIPVVLPGI SSSLACTVLA QIPATQRDIA DQVLICTGTG RKGALPIIPE 

       490        500        510        520        530        540 
FVESRTTVFL MALHRANVLI TGLLKHGWDG DVPAAIVERG SCPDQRVTRT LLKWVPEVVE 

       550        560        570        580        590 
EIGSRPPGVL VVGKAVNALV EKDLINFDES RKFVIDEGFR EFEVDVDSLF KLY 

References and documentation are available.

Number of amino acids: 593

Molecular weight: 66125.24

Theoretical pI: 6.15

Amino acid composition: 
Ala (A)  25	  4.2%
Arg (R)  29	  4.9%
Asn (N)  23	  3.9%
Asp (D)  32	  5.4%
Cys (C)   7	  1.2%
Gln (Q)  22	  3.7%
Glu (E)  44	  7.4%
Gly (G)  44	  7.4%
His (H)  10	  1.7%
Ile (I)  45	  7.6%
Leu (L)  62	 10.5%
Lys (K)  42	  7.1%
Met (M)   9	  1.5%
Phe (F)  27	  4.6%
Pro (P)  34	  5.7%
Ser (S)  39	  6.6%
Thr (T)  35	  5.9%
Trp (W)   6	  1.0%
Tyr (Y)  10	  1.7%
Val (V)  48	  8.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 76
Total number of positively charged residues (Arg + Lys): 71

Atomic composition:

Carbon      C	      2973
Hydrogen    H	      4759
Nitrogen    N	       793
Oxygen      O	       875
Sulfur      S	        16

Formula: C2973H4759N793O875S16
Total number of atoms: 9416

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    48275
Abs 0.1% (=1 g/l)   0.730, assuming all pairs of Cys residues form cystines


Ext. coefficient    47900
Abs 0.1% (=1 g/l)   0.724, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.99
This classifies the protein as stable.



Aliphatic index: 98.06

Grand average of hydropathicity (GRAVY): -0.170