ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVSEGATRKE LNLCFENMKM EGVLISEWKD IPVELLMKIL NLVDDRTVII ASCICSGWRD 

        70         80         90        100        110        120 
AVSLGLTRLS LSWCKKNMNS LVLSLAPKFV KLQTLVLRQD KPQLEDNAVE AIANHCHELQ 

       130        140        150        160        170        180 
DLDLSKSSKI TDHSLYSLAR GCTNLTKLNL SGCTSFSDTA LAHLTRFCRK LKILNLCGCV 

       190        200        210        220        230        240 
EAVSDNTLQA IGENCNQLQS LNLGWCENIS DDGVMSLAYG CPDLRTLDLC SCVLITDESV 

       250        260        270        280        290        300 
VALANRCIHL RSLGLYYCRN ITDRAMYSLA QSGVKNKHEM WRAVKKGKFD EEGLRSLNIS 

       310        320        330        340        350        360 
QCTYLTPSAV QAVCDTFPAL HTCSGRHSLV MSGCLNLQSV HCACILQAHR THTVYPHPAH 

References and documentation are available.

Number of amino acids: 360

Molecular weight: 39909.24

Theoretical pI: 7.45

Amino acid composition: 
Ala (A)  24	  6.7%
Arg (R)  17	  4.7%
Asn (N)  20	  5.6%
Asp (D)  19	  5.3%
Cys (C)  23	  6.4%
Gln (Q)  12	  3.3%
Glu (E)  16	  4.4%
Gly (G)  17	  4.7%
His (H)  13	  3.6%
Ile (I)  16	  4.4%
Leu (L)  53	 14.7%
Lys (K)  19	  5.3%
Met (M)   9	  2.5%
Phe (F)   6	  1.7%
Pro (P)   8	  2.2%
Ser (S)  33	  9.2%
Thr (T)  20	  5.6%
Trp (W)   5	  1.4%
Tyr (Y)   7	  1.9%
Val (V)  23	  6.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 35
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      1730
Hydrogen    H	      2809
Nitrogen    N	       493
Oxygen      O	       523
Sulfur      S	        32

Formula: C1730H2809N493O523S32
Total number of atoms: 5587

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    39305
Abs 0.1% (=1 g/l)   0.985, assuming all pairs of Cys residues form cystines


Ext. coefficient    37930
Abs 0.1% (=1 g/l)   0.950, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.49
This classifies the protein as unstable.



Aliphatic index: 99.94

Grand average of hydropathicity (GRAVY): 0.012