ProtParam
User-provided sequence:
10 20 30 40 50 60
MVSIRRYLRV PNELKPSQIF KQDSLSPSKI GLQIVLLQIF YYTTAIVLFY CWAKLAGYDL
70 80 90 100 110 120
NIKEWLFSWE NIDFTNAYGL SISLLWLLDS LICVFFLTVI VGRSKLAWDF AITIHAINFI
130 140 150 160 170 180
VVFLYTRKFP SFSWFFLQIL SSLILIFLGT WTTRWRELRD TFFEGLVDPN EGEVGLVTPS
190 200
QQHSNHSELE QSPIQLKDLE SQI
References and
documentation are available.
Number of amino acids: 203
Molecular weight: 23715.63
Theoretical pI: 5.91
Total number of negatively charged residues (Asp + Glu): 18
Total number of positively charged residues (Arg + Lys): 16
Atomic composition:
Carbon C 1122
Hydrogen H 1700
Nitrogen N 266
Oxygen O 294
Sulfur S 3
Formula: C
1122H
1700N
266O
294S
3
Total number of atoms: 3385
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 54555
Abs 0.1% (=1 g/l) 2.300, assuming all pairs of Cys residues form cystines
Ext. coefficient 54430
Abs 0.1% (=1 g/l) 2.295, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 47.82
This classifies the protein as unstable.
Aliphatic index: 116.65
Grand average of hydropathicity (GRAVY): 0.338