ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVSMIHIVVF LLAITTMFEI LPLITVPVTK YLSLSSFRNH YYGLFGWCVR GQNQELMCTK 

        70         80         90        100        110        120 
MKIGYDSTDV DSSGHVLTLP SNSKVVVSNL LVVHPISLAF TGTLLILAVI IMVTPLGDSP 

       130        140        150        160        170        180 
EMLLFTALFS LPTFMLCLLC FLVDILLFIS KLDWPGWLML AATISVALCC SMLWVMRRVV 

       190        200        210        220        230 
SVKKYESQQS IAHACSMEQY SISDIYQSKQ NGNSSEYEVA PTHTDSLIAP EVTYRGFIE 

References and documentation are available.

Number of amino acids: 239

Molecular weight: 26696.59

Theoretical pI: 5.82

Amino acid composition: 
Ala (A)  11	  4.6%
Arg (R)   5	  2.1%
Asn (N)   6	  2.5%
Asp (D)   8	  3.3%
Cys (C)   7	  2.9%
Gln (Q)   7	  2.9%
Glu (E)   9	  3.8%
Gly (G)  10	  4.2%
His (H)   6	  2.5%
Ile (I)  18	  7.5%
Leu (L)  33	 13.8%
Lys (K)   8	  3.3%
Met (M)  12	  5.0%
Phe (F)  11	  4.6%
Pro (P)  10	  4.2%
Ser (S)  26	 10.9%
Thr (T)  16	  6.7%
Trp (W)   4	  1.7%
Tyr (Y)   9	  3.8%
Val (V)  23	  9.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 13

Atomic composition:

Carbon      C	      1221
Hydrogen    H	      1923
Nitrogen    N	       291
Oxygen      O	       338
Sulfur      S	        19

Formula: C1221H1923N291O338S19
Total number of atoms: 3792

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    35785
Abs 0.1% (=1 g/l)   1.340, assuming all pairs of Cys residues form cystines


Ext. coefficient    35410
Abs 0.1% (=1 g/l)   1.326, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.22
This classifies the protein as unstable.



Aliphatic index: 115.73

Grand average of hydropathicity (GRAVY): 0.622