ProtParam
User-provided sequence:
10 20 30 40 50 60
MVSQETIKHV KDLIAENEIF VASKTYCPYC HAALNTLFEK LKVPRSKVLV LQLNDMKEGA
70 80 90 100 110
DIQAALYEIN GQRTVPNIYI NGKHIGGNDD LQELRETGEL EELLEPILAN
References and
documentation are available.
Number of amino acids: 110
Molecular weight: 12380.19
Theoretical pI: 4.98
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 11
Atomic composition:
Carbon C 549
Hydrogen H 886
Nitrogen N 146
Oxygen O 170
Sulfur S 4
Formula: C
549H
886N
146O
170S
4
Total number of atoms: 1755
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 6085
Abs 0.1% (=1 g/l) 0.492, assuming all pairs of Cys residues form cystines
Ext. coefficient 5960
Abs 0.1% (=1 g/l) 0.481, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 40.59
This classifies the protein as unstable.
Aliphatic index: 107.27
Grand average of hydropathicity (GRAVY): -0.248