Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVSQETIKHV KDLIAENEIF VASKTYCPYC HAALNTLFEK LKVPRSKVLV LQLNDMKEGA

70 80 90 100 110
DIQAALYEIN GQRTVPNIYI NGKHIGGNDD LQELRETGEL EELLEPILAN


References and documentation are available.

Number of amino acids: 110 Molecular weight: 12380.19 Theoretical pI: 4.98
Amino acid composition: 
Ala (A) 8 7.3% Arg (R) 3 2.7% Asn (N) 8 7.3% Asp (D) 5 4.5% Cys (C) 2 1.8% Gln (Q) 5 4.5% Glu (E) 12 10.9% Gly (G) 6 5.5% His (H) 3 2.7% Ile (I) 9 8.2% Leu (L) 14 12.7% Lys (K) 8 7.3% Met (M) 2 1.8% Phe (F) 2 1.8% Pro (P) 4 3.6% Ser (S) 3 2.7% Thr (T) 5 4.5% Trp (W) 0 0.0% Tyr (Y) 4 3.6% Val (V) 7 6.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 17 Total number of positively charged residues (Arg + Lys): 11 Atomic composition: Carbon C 549 Hydrogen H 886 Nitrogen N 146 Oxygen O 170 Sulfur S 4 Formula: C549H886N146O170S4 Total number of atoms: 1755 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 6085 Abs 0.1% (=1 g/l) 0.492, assuming all pairs of Cys residues form cystines Ext. coefficient 5960 Abs 0.1% (=1 g/l) 0.481, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.59 This classifies the protein as unstable. Aliphatic index: 107.27 Grand average of hydropathicity (GRAVY): -0.248