ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVSSLPKESQ AELQLFQNEI NAANPSDFLQ FSANYFNKRL EQQRAFLKAR EPEFKAKNIV 

        70         80         90        100        110        120 
LFPEPEESFS RPQSAQSQSR SRSSVMFKSP FVNEDPHSNV FKSGFNLDPH EQDTHQQAQE 

       130        140        150        160        170        180 
EQQHTREKTS TPPLPMHFNA QRRTSVSGET LQPNNFDDWT PDHYKEKSEQ QLQRLEKSIR 

       190        200        210        220        230        240 
NNFLFNKLDS DSKRLVINCL EEKSVPKGAT IIKQGDQGDY FYVVEKGTVD FYVNDNKVNS 

       250        260        270        280        290        300 
SGPGSSFGEL ALMYNSPRAA TVVATSDCLL WALDRLTFRK ILLGSSFKKR LMYDDLLKSM 

       310        320        330        340        350        360 
PVLKSLTTYD RAKLADALDT KIYQPGETII REGDQGENFY LIEYGAVDVS KKGQGVINKL 

       370        380        390        400        410 
KDHDYFGEVA LLNDLPRQAT VTATKRTKVA TLGKSGFQRL LGPAVDVLKL NDPTRH 

References and documentation are available.

Number of amino acids: 416

Molecular weight: 47219.09

Theoretical pI: 7.71

Amino acid composition: 
Ala (A)  25	  6.0%
Arg (R)  22	  5.3%
Asn (N)  24	  5.8%
Asp (D)  27	  6.5%
Cys (C)   2	  0.5%
Gln (Q)  27	  6.5%
Glu (E)  27	  6.5%
Gly (G)  20	  4.8%
His (H)   8	  1.9%
Ile (I)  12	  2.9%
Leu (L)  41	  9.9%
Lys (K)  33	  7.9%
Met (M)   6	  1.4%
Phe (F)  24	  5.8%
Pro (P)  22	  5.3%
Ser (S)  36	  8.7%
Thr (T)  22	  5.3%
Trp (W)   2	  0.5%
Tyr (Y)  12	  2.9%
Val (V)  24	  5.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 54
Total number of positively charged residues (Arg + Lys): 55

Atomic composition:

Carbon      C	      2093
Hydrogen    H	      3282
Nitrogen    N	       584
Oxygen      O	       646
Sulfur      S	         8

Formula: C2093H3282N584O646S8
Total number of atoms: 6613

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29005
Abs 0.1% (=1 g/l)   0.614, assuming all pairs of Cys residues form cystines


Ext. coefficient    28880
Abs 0.1% (=1 g/l)   0.612, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.11
This classifies the protein as unstable.



Aliphatic index: 72.43

Grand average of hydropathicity (GRAVY): -0.688