ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVSTQQRTDD DSSQPVKASL KSYGITEPLS IAGPSAADVK RNLELEKFLV DEGLYESKEE 

        70         80         90        100        110        120 
TMRREEVVVR IDQIVKHWVK QLTRQRGYTD QMVEDANAVI FTFGSYRLGV HGPMADIDTL 

       130        140        150        160        170        180 
CVGPSYVNRE EDFFIFFRDI LAEMEEVTEL QPVTDAHVPV MKFKFQGISI DLLYASISLL 

       190        200        210        220        230        240 
VIPQDLDISN SSVLCDVDEQ TVRSLNGCRV ADQILKLVPN SEHFRTTLRC LKYWAKKRGV 

       250        260        270        280        290        300 
YSNVTGFLGG VNWALLVARL CQFYPNAIPS MLVSRFFRVY TQWRWPNPVM LCAIEEDDLS 

       310        320        330        340        350        360 
FPVWDPRKNH RDRYHLMPII TPAYPCMNSS YNVSQSTLRV MTEQFQFGNT ICQEIELNKQ 

       370        380        390        400        410        420 
HWSSLFQQYM FFEAYKNYLQ VDVLAADAED LLAWKGWVES RFRQLTLKIE RDTNGMLMCH 

       430        440        450        460        470        480 
PQPNEYVDTS KQFRHCAFFM GLQRADGFGG QECQQFDIRG TVDEFRQEVN MYMFWRPGMD 

       490        500        510        520        530        540 
VHVSHVRRRQ LPSFVFPNGY KRSRQSRHQS QQCREPGDEG VGSLSDSVER YAKRKNDDEI 

       550        560        570        580        590        600 
MNSRPEKREK RASCSLHTLD AASPDSSGIT TSGTPQIGIV PGPRAECLVT GDLVCNVTSL 

       610        620        630        640        650        660 
PNVEVEAEKF ISKITELRKF SQYEHTSGSE QILEVDSRAL VQSYHDLAEP VAKHVRPDLS 

       670        680        690        700        710        720 
ALLACEGGQN KEIGHDMGSE SINDTDTQHL PRRLNVNEDV DEVEREAKLG EIAGGVLWNG 

       730        740        750        760        770        780 
HCGRNLDHEG FVTPANLDSA VENRNLHSDG LFKSGLPEEL QSNSLLSGTG KLDDGARSES 

       790        800 
LQNEMMRHVF LQPIIGLCKS 

References and documentation are available.

Number of amino acids: 800

Molecular weight: 90967.71

Theoretical pI: 5.43

Amino acid composition: 
Ala (A)  40	  5.0%
Arg (R)  54	  6.8%
Asn (N)  35	  4.4%
Asp (D)  52	  6.5%
Cys (C)  18	  2.2%
Gln (Q)  44	  5.5%
Glu (E)  60	  7.5%
Gly (G)  49	  6.1%
His (H)  22	  2.8%
Ile (I)  34	  4.2%
Leu (L)  71	  8.9%
Lys (K)  33	  4.1%
Met (M)  22	  2.8%
Phe (F)  35	  4.4%
Pro (P)  36	  4.5%
Ser (S)  64	  8.0%
Thr (T)  35	  4.4%
Trp (W)  11	  1.4%
Tyr (Y)  22	  2.8%
Val (V)  63	  7.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 112
Total number of positively charged residues (Arg + Lys): 87

Atomic composition:

Carbon      C	      3995
Hydrogen    H	      6239
Nitrogen    N	      1129
Oxygen      O	      1225
Sulfur      S	        40

Formula: C3995H6239N1129O1225S40
Total number of atoms: 12628

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    94405
Abs 0.1% (=1 g/l)   1.038, assuming all pairs of Cys residues form cystines


Ext. coefficient    93280
Abs 0.1% (=1 g/l)   1.025, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 48.79
This classifies the protein as unstable.



Aliphatic index: 79.03

Grand average of hydropathicity (GRAVY): -0.447