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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVTKHQIEED HLDGATTDPE VKRVKLENNV EEIQPEQAET NKQEGTDKEN KGKFEKETER

70 80 90 100 110 120
IGGSEVVTDV EKGIVKFEFD GVEYTFKERP SVVEENEGKI EFRVVNNDNT KENMMVLTGL

130 140 150 160 170 180
KNIFQKQLPK MPKEYIARLV YDRSHLSMAV IRKPLTVVGG ITYRPFDKRE FAEIVFCAIS

190 200 210 220 230 240
STEQVRGYGA HLMNHLKDYV RNTSNIKYFL TYADNYAIGY FKKQGFTKEI TLDKSIWMGY

250 260 270 280 290 300
IKDYEGGTLM QCSMLPRIRY LDAGKILLLQ EAALRRKIRT ISKSHIVRPG LEQFKDLNNI

310 320 330 340 350 360
KPIDPMTIPG LKEAGWTPEM DALAQRPKRG PHDAAIQNIL TELQNHAAAW PFLQPVNKEE

370 380 390 400 410 420
VPDYYDFIKE PMDLSTMEIK LESNKYQKME DFIYDARLVF NNCRMYNGEN TSYYKYANRL

430
EKFFNNKVKE IPEYSHLID


References and documentation are available.

Number of amino acids: 439 Molecular weight: 51069.34 Theoretical pI: 6.22
Amino acid composition: 
Ala (A) 22 5.0% Arg (R) 22 5.0% Asn (N) 27 6.2% Asp (D) 24 5.5% Cys (C) 3 0.7% Gln (Q) 16 3.6% Glu (E) 44 10.0% Gly (G) 24 5.5% His (H) 9 2.1% Ile (I) 31 7.1% Leu (L) 31 7.1% Lys (K) 42 9.6% Met (M) 15 3.4% Phe (F) 19 4.3% Pro (P) 20 4.6% Ser (S) 15 3.4% Thr (T) 24 5.5% Trp (W) 3 0.7% Tyr (Y) 22 5.0% Val (V) 26 5.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 68 Total number of positively charged residues (Arg + Lys): 64 Atomic composition: Carbon C 2285 Hydrogen H 3581 Nitrogen N 611 Oxygen O 680 Sulfur S 18 Formula: C2285H3581N611O680S18 Total number of atoms: 7175 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 49405 Abs 0.1% (=1 g/l) 0.967, assuming all pairs of Cys residues form cystines Ext. coefficient 49280 Abs 0.1% (=1 g/l) 0.965, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.82 This classifies the protein as unstable. Aliphatic index: 77.27 Grand average of hydropathicity (GRAVY): -0.653