Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVTQTNPVPV TYPTDAYIPT YLPDDKVSNL ADLKKLIEMD SRLDLYLTRR RLDTSINLPT

70 80 90 100 110 120
NTKTKDHPPN KEMLRIYVYN TTESSPRSDS GTPADSGKTT WTLRIEGKLL HESANGKHPF

130 140 150 160 170 180
SEFLEGVAVD FKRLKPLGMG KKRKRDSSLS LPLNLQQPEY NDQDSTMGDN DNGEDEDSAE

190 200 210 220 230 240
AESREEIVDA LEWNYDENNV VEFDGIDIKR QGKDNLRCSI TIQLRGVDGG KVQYSPNLAT

250 260 270 280 290 300
LIGMQTGSVN DAVYSIYKYI LINNLFVTEQ TEAQDGSNDA EDSSNENNNK NGAGDDDGVE

310 320 330 340 350 360
GSTPKDKPEL GEVKLDSLLQ KVLDTNAAHL PLMNVVQTVN KLVSPLPPII LDYTIDLSKD

370 380 390 400 410 420
TTYGATTLDV DVSHILHQPQ PQPNLQKEEE TDAEDTAKLR EITKLALQLN SSAQKYQFFH

430 440 450 460 470 480
ELSLHPRETL THYLWSSKQN ELVLQGDQYF NEDAARTSDI YSNNNNDRSL MGNISLLYSQ


GRL


References and documentation are available.

Number of amino acids: 483 Molecular weight: 54164.98 Theoretical pI: 4.69
Amino acid composition: 
Ala (A) 22 4.6% Arg (R) 19 3.9% Asn (N) 37 7.7% Asp (D) 45 9.3% Cys (C) 1 0.2% Gln (Q) 23 4.8% Glu (E) 33 6.8% Gly (G) 26 5.4% His (H) 9 1.9% Ile (I) 21 4.3% Leu (L) 55 11.4% Lys (K) 30 6.2% Met (M) 8 1.7% Phe (F) 8 1.7% Pro (P) 25 5.2% Ser (S) 38 7.9% Thr (T) 36 7.5% Trp (W) 3 0.6% Tyr (Y) 19 3.9% Val (V) 25 5.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 78 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 2357 Hydrogen H 3731 Nitrogen N 651 Oxygen O 793 Sulfur S 9 Formula: C2357H3731N651O793S9 Total number of atoms: 7541 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 44810 Abs 0.1% (=1 g/l) 0.827, assuming all pairs of Cys residues form cystines Ext. coefficient 44810 Abs 0.1% (=1 g/l) 0.827, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.42 This classifies the protein as unstable. Aliphatic index: 80.93 Grand average of hydropathicity (GRAVY): -0.744